The evaluation of hemostatic dysfunction and disseminated intravascular coagulation in dairy cows with abomasal displacement

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dc.contributor.authorMaden, M.
dc.contributor.authorYildiz, R.
dc.contributor.authorCol, R.
dc.contributor.authorArican, M.
dc.contributor.authorIder, M.
dc.contributor.authorGarip, M.
dc.contributor.authorTras, B.
dc.date.accessioned2020-03-26T19:56:17Z
dc.date.available2020-03-26T19:56:17Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractDisseminated intravascular coagulation (DIC) is a complex, dynamic and hemostatic disorder which develops secondarily to a disease characterized with an imbalance in the pro-coagulant and anti-coagulant components of hemostasis. The aim of the study is to evaluate hemostatic dysfunction and the DIC syndrome in cattle with displaced abomasum (DA), with using the hematologic analyses and an extensive coagulation profile in the 96 hour-period including before and after surgery. The animal material of the study consisted of 12 dairy cows diagnosed with displaced abomasum (9 LDA and 3 RDA without volvulus) in the 2-4 week period after parturation and with no other post-partum disease. In dairy cows diagnosed with DA, hematological, coagulometric (PT, APTT, Fibrinogen) and coagulation factor analyses [D-Dimer, TAT (thrombin-antithrombin complex), ATIII (antithrombin III), PAI-1 (plazminogen activator inhibitor-1] were performed in blood samples obtained before the operation as well as 30 minutes, 60 minutes and 2, 5, 10, 24, 48, 72 and 96 hours after the operation. In the DA cases, abnormalities were found in 6 of the 8 coagulation parameters. In the LDA and RDA groups, prolonged PT (sec), PT (INR) and APTT, hypofibrinogenemia, an increase in serum D-Dimer concentration at 72 and 96 hours after the operation and an increase in serum ATIII concentrations before and 30, 60 minutes and 2, 5, 72 and 96 hours after the operation was found (p<0.05). Hemostatic dysfunction and the risk of DIC developing in DA cases and continuing in the post-operative period was determined.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [112O398]; Selcuk University Scientific Research Projects Coordination Unit (BAP) [13401077]en_US
dc.description.sponsorshipThis study was supported by The Scientific and Technological Research Council of Turkey (TUBITAK, 112O398) and Selcuk University Scientific Research Projects Coordination Unit (BAP, 13401077).en_US
dc.identifier.doi10.24425/pjvs.2018.125590en_US
dc.identifier.endpage778en_US
dc.identifier.issn1505-1773en_US
dc.identifier.issn2300-2557en_US
dc.identifier.issue4en_US
dc.identifier.pmid30605273en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage769en_US
dc.identifier.urihttps://dx.doi.org/10.24425/pjvs.2018.125590
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37040
dc.identifier.volume21en_US
dc.identifier.wosWOS:000455928100015en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPOLSKA AKAD NAUK, POLISH ACAD SCIENCES, UNIV WARMIA & MAZURY OLSZTYNen_US
dc.relation.ispartofPOLISH JOURNAL OF VETERINARY SCIENCESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectDICen_US
dc.subjecthemostatic dysfunctionen_US
dc.subjectLDAen_US
dc.subjectRDAen_US
dc.subjectdairy cowen_US
dc.titleThe evaluation of hemostatic dysfunction and disseminated intravascular coagulation in dairy cows with abomasal displacementen_US
dc.typeArticleen_US

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