Morphometric Effect of Nandrolone Decanoate Used as Doping in Sport on Femur of Rats in Puberty Period

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dc.contributor.authorLök, Sefa
dc.contributor.authorYalçın, Hakan
dc.date.accessioned2020-03-26T18:04:42Z
dc.date.available2020-03-26T18:04:42Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground The aim of this research is to show the morphometric effect of nandrolone that is used as doping in sport on femur of rats in puberty period. Material/Methods: A total of 60 Sprague-Dawley rats (30 days old) were divided into three equal groups. The control group (male n = 10, female n = 10) was nourished for 4 weeks without any substance being administered. For the peanut oil group (male n = 10, female n = 10), peanut oil was used as diluent of nandrolone decanoate (500 mcl). It was administered for 5 days via intraperitoneal injection, with a pause of 2 days and the same application was done for 4 weeks.. Nandrolone decanoate was applied for 5 days to the Nandrolone group (male n = 10, female n = 10) in 10 mg/kg dose by being diluted in 500 mcl peanut oil via intraperitoneal injection and the same was applied for 4 weeks having taken a 2-day long pause. Rats were euthanatized at the end of fourth week. Back extremity bones of materials were revealed by being dissected and put to maceration operation. Results: Morphometric measures were taken by determining the anatomic reference points (length, corpus, cortex-cortical bone thickness-substantiate compact, medullar wide-cavity medullar) that would be measured of femur bones that are on right side. It was determined that nandrolone caused shortening in femur length (p<0.05) in male and female rats when compared to peanut oil and control groups. Conclusions: Nandrolone may delay the bone formation in the puberty period.en_US
dc.description.sponsorshipSelcuk UniversitySelcuk University [09-202021]en_US
dc.description.sponsorshipThis study is a portion of Ph thesis and is supported by Selcuk University Scientific Research Projects Coordinator (SUBAPK, 09-202021).en_US
dc.identifier.citationLök, S., Yalçın, H., (2010). Morphometric Effect of Nandrolone Decanoate Used as Doping in Sport on Femur of Rats in Puberty Period. Archives of Budo, 6(4), 217-220.
dc.identifier.endpage220en_US
dc.identifier.issn1643-8698en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage217en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/25084
dc.identifier.volume6en_US
dc.identifier.wosWOS:000286476100001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorYalçın, Hakan
dc.language.isoenen_US
dc.publisherINT SCIENTIFIC INFORMATION, INCen_US
dc.relation.ispartofArchives of Budoen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectNandroloneen_US
dc.subjectMorphometricen_US
dc.subjectFemuren_US
dc.titleMorphometric Effect of Nandrolone Decanoate Used as Doping in Sport on Femur of Rats in Puberty Perioden_US
dc.typeArticleen_US

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