Multicenter Analysis of Gestational Trophoblastic Neoplasia in Turkey

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dc.contributor.authorOzalp, Sabit Sinan
dc.contributor.authorTelli, Elcin
dc.contributor.authorOge, Tufan
dc.contributor.authorTulunay, Gokhan
dc.contributor.authorBoran, Nurettin
dc.contributor.authorTuran, Taner
dc.contributor.authorYenen, Mufit
dc.date.accessioned2020-03-26T18:51:39Z
dc.date.available2020-03-26T18:51:39Z
dc.date.issued2014
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: To evaluate the incidence, diagnosis and management of GTN among 28 centers in Turkey. Materials and Methods: A retrospective study was designed to include GTN patients attending 28 centers in the 10-year period between January 2003 and May 2013. Demographical characteristics of the patients, histopathological diagnosis, the International Federation of Gynecology and Obstetrics (FIGO) anatomical and prognostic scores, use of single-agent and multi-agent chemotherapy, surgical interventions and prognosis were evaluated. Results: From 2003-2013, there were 1,173,235 deliveries and 456 GTN cases at the 28 centers. The incidence was calculated to be 0.38 per 1,000 deliveries. According to the evaluated data of 364 patients, the median age at diagnosis was 31 years (range, 15-59 years). A histopathological diagnosis was present for 45.1% of the patients, and invasive mole, choriocarcinoma and PSTTs were diagnosed in 22.3% (n=81), 18.1% (n=66) and 4.7% (n=17) of the patients, respectively. Regarding final prognosis, 352 (96.7%) of the patients had remission, and 7 (1.9%) had persistence, whereas the disease was mortal for 5 (1.4%) of the patients. Conclusions: Because of the differences between countries, it is important to provide national registration systems and special clinics for the accurate diagnosis and treatment of GTN.en_US
dc.identifier.doi10.7314/APJCP.2014.15.8.3625en_US
dc.identifier.endpage3628en_US
dc.identifier.issn1513-7368en_US
dc.identifier.issue8en_US
dc.identifier.pmid24870768en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage3625en_US
dc.identifier.urihttps://dx.doi.org/10.7314/APJCP.2014.15.8.3625
dc.identifier.urihttps://hdl.handle.net/20.500.12395/31009
dc.identifier.volume15en_US
dc.identifier.wosWOS:000338633500049en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherASIAN PACIFIC ORGANIZATION CANCER PREVENTIONen_US
dc.relation.ispartofASIAN PACIFIC JOURNAL OF CANCER PREVENTIONen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectGestational trophoblastic diseaseen_US
dc.subjectgestational trophoblastic neoplasiaen_US
dc.subjectincidenceen_US
dc.subjectTurkeyen_US
dc.titleMulticenter Analysis of Gestational Trophoblastic Neoplasia in Turkeyen_US
dc.typeArticleen_US

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