Synthesis of novel ferrocene containing vic-dioxime ligands and their Ni(II), Cu(II) and Co(II) complexes: Spectral, electrochemical and biological activity studies

Küçük Resim Yok

Tarih

2011

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

ELSEVIER SCIENCE SA

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Two new vic-dioxime ligands bearing an important redox-active substituent, anti-beta-ferrocenylethylaminoglyoxime (1a) and anti-beta-ferrocenylethylaminophenylglyoxime (1b), have been synthesized, and their Ni(II), Cu(II) and Co(II) (2a-4a, 2b-4b) complexes were obtained. The composition and structure of the products were determined by elemental analysis, Fourier transform infrared (FT-IR), ultraviolet-visible (UV-vis), mass spectrometry (MS), one-dimensional (1D) H-1, C-13 NMR, and two-dimensional (2D) heteronuclear multiple bond correlation (HMBC) techniques. The redox behaviors of the ligands and their complexes were investigated by cyclic voltammetry (CV), which revealed that all the ferrocenyl redox centers are electrochemically independent and undergo a quasi-reversible oxidation at similar potentials. Also, antibacterial activity was studied against Staphylococcus aureus ATCC 29213, Streptococcus mutans RSHM 676, Enterococcus faecalis ATCC 29212, Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853. The antimicrobial test results indicated that all the compounds have mild levels of antibacterial activity against both gram negative and gram-positive bacterial species. (C) 2011 Elsevier B.V. All rights reserved.

Açıklama

Anahtar Kelimeler

vic-Dioxime, Ferrocene, Electrochemical study, Biological activity, Metal complex

Kaynak

JOURNAL OF ORGANOMETALLIC CHEMISTRY

WoS Q Değeri

Q2

Scopus Q Değeri

Q3

Cilt

696

Sayı

23

Künye