Cerebral venous sinus thrombosis in an adolescent with Ewing sarcoma

dc.contributor.authorUnal, Ekrem
dc.contributor.authorYazar, Abdullah
dc.contributor.authorKoksal, Yavuz
dc.contributor.authorCaliskan, Umran
dc.contributor.authorPaksoy, Yahya
dc.contributor.authorKalkan, Erdal
dc.date.accessioned2020-03-26T17:26:28Z
dc.date.available2020-03-26T17:26:28Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground Although thromboembolic complications are common in adult patients with malignant diseases, cerebral venous sinus thrombosis has been rarely described in cancer afflicted pediatric and adolescent population. Case history A 16-year-old adolescent girl referred for complaints of pain and swelling on her left leg. On physical examination, a solid tibial mass was discovered. After the diagnosis of Ewing sarcoma with a tru-cut biopsy, chemotherapy protocol consisting of cisplatin, ifosfamide, adriamycine, and vincristine was started. During the first course of the treatment, the patient expressed headache, diplopia, and ptosis. Contrast-enhanced magnetic resonance (MR) images and MR angiography showed superior sagittal and transverse sinus thromboses. After anticoagulant therapy, the thromboses disappeared within 1.5 months. She received her chemotherapy protocol with the anticoagulant prophylaxis. After a follow-up period of 12 months, she is still in a good neurological recovery without any sequel. Conclusion Children and adolescents with cancer should be monitored closely for thrombotic complications. We discuss this uncommon case to draw attention to the importance of early diagnosis and adequate treatment of intracranial thrombosis in childhood cancer, and we review the relevant literature.en_US
dc.identifier.doi10.1007/s00381-008-0646-0en_US
dc.identifier.endpage986en_US
dc.identifier.issn0256-7040en_US
dc.identifier.issn1433-0350en_US
dc.identifier.issue9en_US
dc.identifier.pmid18481071en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage983en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s00381-008-0646-0
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22241
dc.identifier.volume24en_US
dc.identifier.wosWOS:000258315100002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.relation.ispartofCHILDS NERVOUS SYSTEMen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectchildrenen_US
dc.subjectEwing sarcomaen_US
dc.subjectintracranial venous sinus thrombosisen_US
dc.titleCerebral venous sinus thrombosis in an adolescent with Ewing sarcomaen_US
dc.typeArticleen_US

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