Omental Transposition Decreases Ischemic Brain Damage Examined in a New Ischemia Model
dc.contributor.author | Vatansev, Celalettin | |
dc.contributor.author | Üstün, M. E. | |
dc.contributor.author | Öğün, C. O. | |
dc.contributor.author | Taştekin, G. | |
dc.contributor.author | Karabacakoğlu, A. | |
dc.contributor.author | Yılmaz, H. | |
dc.date.accessioned | 2020-03-26T16:45:55Z | |
dc.date.available | 2020-03-26T16:45:55Z | |
dc.date.issued | 2003 | |
dc.department | Selçuk Üniversitesi | en_US |
dc.description.abstract | Purpose:The aim of this study was to determine whether omental transposition at the time of focal cerebral ischemia can decrease ischemic brain damage produced in dogs, in a new ischemia model, which had been described by us. Methods: In group 1 (n = 5), the left internal carotid artery and arterial circle of the brain (posterior communicating artery in humans) were occluded permanently. In group 2 (n = 5), additionally to this ischemia model, omental transposition was performed simultaneously. In the postoperative early period (first 24 h), single photon emission computed tomography (SPECT) and in the late period (72-96 h) SPECT and magnetic resonance imaging (MRI) of the brain were performed. Mann-Whitney U, paired t and Wilcoxon signed rank tests were used for statistical analyses, and p < 0.05 was considered significant. Results: The dogs had a neurological score (NS) of 3.6 +/- 0.5 and 3.4 +/- 0.5 in groups 1 and 2, respectively, in the early period (p > 0.05). In the late period, the dogs had an NS of 4.4 +/- 0.5 and 5.6 +/- 0.5 in groups 1 and 2, respectively (p < 0.05). The NS of each group differed significantly between the early and late period (p < 0.05). Early SPECT imaging showed 50 7.0% and 52 +/- 8.4% hypoperfusion corresponding to the left middle cerebral artery territory in groups 1 and 2, respectively (p > 0.05). In the late period, the degree of hypoperfusion decreased to 34 +/- 5.5% and 12 +/- 4.8% in groups 1 and 2, respectively (p < 0.05). The degree of hypoperfusion in both groups changed significantly between the early and late period (p < 0.05). In T-1- and T-2-weighted MRI images, the volume of the lesion in group 1 was significantly greater than in group 2 (p < 0.001). Conclusion: In our new ischemia model, simultaneous omental transposition is helpful in reversing the neurologic deficit and cerebral ischemic damage. | en_US |
dc.identifier.citation | Vatansev, C., Üstün, M. E., Öğün, C. O., Taştekin, G., Karabacakoğlu, A., Yılmaz, H., (2003). Omental Transposition Decreases Ischemic Brain Damage Examined in a New Ischemia Model. European Surgical Research, (35), 388-394. Doi: 10.1159/000070612 | |
dc.identifier.doi | 10.1159/000070612 | en_US |
dc.identifier.endpage | 394 | en_US |
dc.identifier.issn | 0014-312X | en_US |
dc.identifier.pmid | 12802102 | en_US |
dc.identifier.scopusquality | Q3 | en_US |
dc.identifier.startpage | 388 | en_US |
dc.identifier.uri | https://dx.doi.org/10.1159/000070612 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12395/18518 | |
dc.identifier.volume | 35 | en_US |
dc.identifier.wos | WOS:000183887300010 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.institutionauthor | Vatansev, Celalettin | |
dc.institutionauthor | Üstün, M. E. | |
dc.institutionauthor | Öğün, C. O. | |
dc.institutionauthor | Taştekin, G. | |
dc.institutionauthor | Karabacakoğlu, A. | |
dc.institutionauthor | Yılmaz, H. | |
dc.language.iso | en | en_US |
dc.publisher | Karger | en_US |
dc.relation.ispartof | European Surgical Research | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.selcuk | 20240510_oaig | en_US |
dc.subject | Cerebral İschemia | en_US |
dc.subject | Omental Transposition | en_US |
dc.subject | Single Photon Emission Computed Tomography | en_US |
dc.subject | Magnetic Resonance İmaging | en_US |
dc.subject | Experimental Model | en_US |
dc.title | Omental Transposition Decreases Ischemic Brain Damage Examined in a New Ischemia Model | en_US |
dc.type | Article | en_US |
Dosyalar
Orijinal paket
1 - 1 / 1
Yükleniyor...
- İsim:
- vatansev2003 (1).pdf
- Boyut:
- 191.77 KB
- Biçim:
- Adobe Portable Document Format
- Açıklama:
- Makale Dosyası