Absence of Increase in Carotid Artery Intima-Media Thickness in Infants of Diabetic Mothers

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dc.contributor.authorAtabek, Mehmet Emre
dc.contributor.authorCagan, Havva Hasret
dc.contributor.authorEklioglu, Beray Selver
dc.contributor.authorOran, Bulent
dc.date.accessioned2020-03-26T18:13:42Z
dc.date.available2020-03-26T18:13:42Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: Infants of diabetic mothers (IDM) are considered as a risk group for atherosclerosis. Increased aortic intima-media thickness has been reported in IDM. The purpose of this study was to assess carotid artery intima-media thickness (CA-IMT), left ventricular mass index (LVMI) and atherosclerotic risk factors in IDM. Methods: Thirty IDM and 25 healthy controls were included in the study. Of these infants, 14 were appropriate-for-gestational age (AGA) and 16 were large-for-gestational age (LGA). CA-IMT and LVMI were obtained by M-mode echocardiographic examination. The relationship between parameters of atherosclerosis and echocardiographic measurements was assessed by Pearson's correlation analysis. Results: LVMI was higher in LGA IDM when compared to AGA IDM and controls. CA-IMT was not significantly different between the groups and was also not related to atherosclerotic risk factors. Serum lipid and insulin levels were higher in LGA IDM when compared with AGA IDM and controls. There were no correlations between CA-IMT, LVMI and atherosclerotic risk factors. Conclusions: In contrast to previous reports indicating an increase in CA-IMT in IDM, no differences were found between IDM and controls in this study. Our results indicate that macrosomic IDM are prone to hypertrophic cardiomyopathy but not to atherosclerotic changes in the blood vessels.en_US
dc.identifier.doi10.4274/jcrpe.v3i3.28en_US
dc.identifier.endpage148en_US
dc.identifier.issn1308-5727en_US
dc.identifier.issn1308-5735en_US
dc.identifier.issue3en_US
dc.identifier.pmid21911328en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage144en_US
dc.identifier.urihttps://dx.doi.org/10.4274/jcrpe.v3i3.28
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26084
dc.identifier.volume3en_US
dc.identifier.wosWOS:000497376700007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGALENOS YAYINCILIKen_US
dc.relation.ispartofJOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGYen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectIntima-media thicknessen_US
dc.subjectleft ventricular massen_US
dc.subjectmacrosomic newbornsen_US
dc.titleAbsence of Increase in Carotid Artery Intima-Media Thickness in Infants of Diabetic Mothersen_US
dc.typeBook Chapteren_US

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