Chemical composition and anti-inflammatory activity of Kitaibelia balansae boiss

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dc.contributor.authorKaratoprak, Gökçe Şeker.
dc.contributor.authorPaşayeva, Leyla.
dc.contributor.authorKöngül Şafak, Esra.
dc.contributor.authorGöger, Fatih.
dc.contributor.authorTugay, Osman.
dc.contributor.authorKoşar, Müberra.
dc.date.accessioned2020-03-26T20:12:53Z
dc.date.available2020-03-26T20:12:53Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümüen_US
dc.description.abstractAerial part extracts of Kitaibelia balansae Boiss. were examined for their phenolic contents, as well as anti-inflammatory activities. The chemical compositions of the extracts were analysed by spectrophotometric and chromatographic (HPLC/ MS/MS and HPLC-PDA) approaches. To measure anti-inflammatory activity, the effects of the extracts on nitric oxide (NO) and Tumour Necrosis Factor-alpha (TNF-alpha) levels were measured in lipopolysaccharide (LPS) treated murine macrophage cell line (RAW 264.7). The ethyl acetate fraction was found to be abundant in phenolic compounds (259.78 +/- 15.07 mg(GAE)/gextract). Rutin was identified as the major compound in all the extracts. The ethyl acetate fraction potentially inhibited NO and TNF-alpha production (37.26 mu M and 1781.524 pg/mL, respectively, 6 h) in LPS induced cells.en_US
dc.description.sponsorshipErciyes University Scientific Research ProjectsErciyes University [THD-2016-6600]en_US
dc.description.sponsorshipErciyes University Scientific Research Projects (THD-2016-6600) supported this research.en_US
dc.identifier.citationKaratoprak, G. Ş., Paşayeva, L., Şafak, E. K., Göger, F., Tugay, O., Koşar, M. (2019). Chemical Composition and Anti-Inflammatory Activity of Kitaibelia balansae Boiss. Farmacia, 67(6), 1054-1059.
dc.identifier.doi10.31925/farmacia.2019.6.17en_US
dc.identifier.endpage1059en_US
dc.identifier.issn0014-8237en_US
dc.identifier.issn2065-0019en_US
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1054en_US
dc.identifier.urihttps://dx.doi.org/10.31925/farmacia.2019.6.17
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37569
dc.identifier.volume67en_US
dc.identifier.wosWOS:000510208600017en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorTugay, Osman.
dc.language.isoenen_US
dc.publisherSOC STIINTE FARMACEUTICE ROMANIAen_US
dc.relation.ispartofFARMACIAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectKitaibelia balansaeen_US
dc.subjectMalvaceaeen_US
dc.subjectHPLC/MS/MSen_US
dc.subjectanti-inflammatoryen_US
dc.titleChemical composition and anti-inflammatory activity of Kitaibelia balansae boissen_US
dc.typeArticleen_US

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