The Clinical Value of Preoperative and Intraoperative Assessments in the Management of Endometrial Cancer

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dc.contributor.authorÇelik, Çetin
dc.contributor.authorÖzdemir, Suna
dc.contributor.authorEsen, Hasan
dc.contributor.authorBalcı, Osman
dc.contributor.authorYılmaz, Osman
dc.date.accessioned2020-03-26T18:05:09Z
dc.date.available2020-03-26T18:05:09Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: In this study, we aimed to investigate the diagnostic accuracy of preoperative assessment and frozen-section analysis (FSA) in endometrial cancer by comparing postoperative histopathology. Methods: A total of 72 consecutive patients with endometrial cancer were included in this study. Comprehensive surgical staging was performed in all patients. After abdominal hysterectomy, the uterus was investigated for FSA. For preoperative analysis, histological grade and histological subtypes were investigated. In FSA, all the specimens were reviewed for histological subtype, histological grade, depth of myometrial invasion, lymphovascular space invasion (LVI), and cervical involvement. These results were compared with final histopathology. Data were statistically analyzed. Results: The accuracy of preoperative examination was 95.8% (69/72) for histological type and 90% (65/72) for histological grade. In the frozen section, the accuracies of histological grade and subtype were found to be 92% and 98%, respectively. However, histological grade had 43% sensitivity in preoperative and intraoperative assessments. Myometrial invasion and LVI were correctly diagnosed in 93% and 94% of the cases, respectively. The risk assessment was correctly determined in 63 (87%) of 72 patients. Five patients were underclassified, and there was no lymph node invasion in these patients after final histopathology. Lymph node invasion was higher in patients with grade 3 classification, deep myometrial invasion, positive cervical involvement, and LVI. Conclusions: Frozen-section analysis is a feasible method for the management of the patients with endometrial cancer. However, preoperative and intraoperative assessment of histological grade has lower sensitivity in endometrial cancer.en_US
dc.identifier.citationÇelik, Ç., Özdemir, S., Esen, H., Balcı, O., Yılmaz, O., (2010). The Clinical Value of Preoperative and Intraoperative Assessments in the Management of Endometrial Cancer. International Journal of Gynecological Cancer, 20(3), 358-362. DOI: 10.1111/IGC.0b013e3181cff1f3
dc.identifier.doi10.1111/IGC.0b013e3181cff1f3en_US
dc.identifier.endpage362en_US
dc.identifier.issn1048-891Xen_US
dc.identifier.issn1525-1438en_US
dc.identifier.issue3en_US
dc.identifier.pmid20375797en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage358en_US
dc.identifier.urihttps://dx.doi.org/10.1111/IGC.0b013e3181cff1f3
dc.identifier.urihttps://hdl.handle.net/20.500.12395/25325
dc.identifier.volume20en_US
dc.identifier.wosWOS:000276899900008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÇelik, Çetin
dc.institutionauthorÖzdemir, Suna
dc.institutionauthorEsen, Hasan
dc.institutionauthorBalcı, Osman
dc.institutionauthorYılmaz, Osman
dc.language.isoenen_US
dc.publisherLIPPINCOTT WILLIAMS & WILKINSen_US
dc.relation.ispartofInternational Journal of Gynecological Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectEndometrial Canceren_US
dc.subjectPreoperative Assessmenten_US
dc.subjectFrozen Sectionen_US
dc.subjectManagementen_US
dc.titleThe Clinical Value of Preoperative and Intraoperative Assessments in the Management of Endometrial Canceren_US
dc.typeArticleen_US

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