Investigation of the Effects of Melatonin and Steroid (st) in Preventing of Testicular Atrophy After Surgical Management Performed with Fowler-Stephens Procedure of Intraabdominal Testis in Late Period

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dc.authorid0000-0002-5783-7181
dc.authorid0000-0002-6638-521X
dc.authorid0000-0001-9667-6029
dc.authorid0000-0002-8709-8949
dc.authorid0000-0003-4972-3405
dc.contributor.authorYurtçu, Müslim
dc.contributor.authorAbasıyanık, Adnan
dc.contributor.authorGökçe, Recep
dc.contributor.authorAvınduk, Mustafa Cihat
dc.contributor.authorÖzdamar, Mustafa Yaşar
dc.date.accessioned2020-03-26T17:28:36Z
dc.date.available2020-03-26T17:28:36Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesi, Meram Tıp Fakültesi, Çocuk Cerrahisi Anabilim Dalıen_US
dc.description.abstractAim: Identifying of the effects of melatonin (M) and steroid St) which prevents testicular atrophy at the surgical treatment of intraabdominal testes with the procedure of Fowler-Stephens (FS). Material and Method: The vessels of right funiculus spermaticus (FSP) of rats, except in Sham (S) group, were ligated and cut under the kidney (KD) with intraabdominal procedure. The vessels of FSP were ligated and cut under the KD in Control (FS) group. St and M groups were injected intramuscularly with steroid at 2 mg/kg; intraperitoneally with M 17 ?g/kg 30 minutes before cutting the vessels of FSP under the KD. St and M injections were continued for 7 days in seven-dose St and seven-dose M groups respectively. All tissues were examined for the levels of MDA (malondialdehyde) and JS (Johnsen's score) after weighing them. The levels of follicule stimulam hormon (FSH), luteotrope hormon (LH), and free testosteron (FT) in blood were measured. Results: The values of FSH were significantly higher in S group compared with One-dose M group. The levels of MDA were identified to be increased in One-dose St group compared with Seven-dose St group, to be decreased in One-dose St group compared with One-dose M group and in Seven-dose St group compared with Seven-dose M group. The values of JS in S group were higher compared with FS group. Conclusions: One-dose and seven-dose St and M have positive effect regarding JS. MDA was identified to be decreased with seven-dose steroid. As a result M and St seem to be effective in preventing testicular atrophy and injury occurred due to FS.en_US
dc.identifier.citationYurtçu, M., Abasıyanık, A., Gökçe, R., Avınduk, M. C., Özdamar, M. Y. (2008). İntraandominal testislerin fowler-stephens yöntemi ile yapılan cerrahi tedavisinden sonra gelişen testis atrofisini önlemede melatonin ve steroidin uzun dönem etkilerinin araştırılması. Çocuk Cerrahisi Dergisi, 22, (1), 33 - 38.
dc.identifier.endpage38en_US
dc.identifier.issn1305-5194en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage33en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22812
dc.identifier.volume22en_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorYurtçu, Müslim
dc.institutionauthorAbasıyanık, Adnan
dc.institutionauthorGökçe, Recep
dc.institutionauthorAvınduk, Mustafa Cihat
dc.institutionauthorÖzdamar, Mustafa Yaşar
dc.language.isotren_US
dc.relation.ispartofÇocuk Cerrahisi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectFowler-Stephensen_US
dc.subjectIntraabdominal testesen_US
dc.subjectJohnsen's scoreen_US
dc.titleInvestigation of the Effects of Melatonin and Steroid (st) in Preventing of Testicular Atrophy After Surgical Management Performed with Fowler-Stephens Procedure of Intraabdominal Testis in Late Perioden_US
dc.title.alternativeİntraabdominal Testislerin Fowler-Stephens Yöntemi ile Yapılan Cerrahi Tedavisinden Sonra Gelişen Testis Atrofisini Önlemede Melatonin ve Steroidin Uzun Dönem Etkilerinin Araştırılmasıen_US
dc.typeArticleen_US

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