Assessment of subclinical atherosclerosis in vitamin D deficiency

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dc.contributor.authorAydın, Elçin
dc.contributor.authorAltın, Cihan
dc.contributor.authorSöylev, Gözde Özcan
dc.contributor.authorTekindal, Mustafa Agah
dc.contributor.authorAğıldere, Muhteşem
dc.date.accessioned2020-03-26T20:12:38Z
dc.date.available2020-03-26T20:12:38Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose Patients with vitamin D deficiency (VDD) have potential to have increased cardiovascular morbidity and mortality. In this study, we aimed to discover the findings of early atherosclerosis in patients with VDD by measuring carotid intima-media thickness (CIMT) and epicardial fat thickness (EFT). Materials and Methods The study population includes 52 patients with VDD (n = 30 [57% female], mean +/- SD age 54.28 +/- 8.77 years, mean +/- SD serum 25-hydroxyvitamin D (25 [OH] D) 11 +/- 2.4 ng/mL) and 82 participants for control group (n = 52 [63.4% female], mean +/- SD age 56.40 +/- 7.90 years, mean +/- SD serum (25 [OH] D) 53 +/- 4.2 ng/mL) who have no cardiovascular disease. Carotid intima-media thickness was assessed by using ultrasonography, and EFT was measured on the free wall of the right ventricle at end diastole from the parasternal long-axis views by standard transthoracic 2-dimensional echocardiography. Results Both CIMT and EFT were significantly higher in patients with VDD compared with controls (0.75 +/- 0.16 mm vs 0.68 +/- 0.21 mm, P < 0.05, and 0.66 +/- 0.15 cm vs 0.56 +/- 0.15 cm, P < 0.001). Conclusions Patients with VDD seem to have increased CIMT and EFT, which are predictors of atherosclerotic process. Further studies are needed to confirm these results.en_US
dc.identifier.citationAydın, E., Altın, C., Söylev, G. Ö., Tekindal, M. A., Ağıldere, M. (2019). Assessment of Subclinical Atherosclerosis in Vitamin D Deficiency. Ultrasound Quarterly, 35(2), 142-146.
dc.identifier.doi10.1097/RUQ.0000000000000386en_US
dc.identifier.endpage146en_US
dc.identifier.issn0894-8771en_US
dc.identifier.issn1536-0253en_US
dc.identifier.issue2en_US
dc.identifier.pmid30300321en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage142en_US
dc.identifier.urihttps://dx.doi.org/10.1097/RUQ.0000000000000386
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37509
dc.identifier.volume35en_US
dc.identifier.wosWOS:000474131600008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTekindal, Mustafa Agah.
dc.language.isoenen_US
dc.publisherLIPPINCOTT WILLIAMS & WILKINSen_US
dc.relation.ispartofULTRASOUND QUARTERLYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectvitamin Den_US
dc.subjectatherosclerosisen_US
dc.subjectcarotid intima-media thicknessen_US
dc.subjectepicardial fat thicknessen_US
dc.titleAssessment of subclinical atherosclerosis in vitamin D deficiencyen_US
dc.typeArticleen_US

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