Leptin and breast cancer: an overview

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dc.contributor.authorArtaç, Mehmet
dc.contributor.authorAltundağ, Kadri
dc.date.accessioned2020-03-26T18:30:48Z
dc.date.available2020-03-26T18:30:48Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractLeptin is a well-known mediator of obesity. Leptin and its receptor are overexpressed in breast cancer, especially in high-grade tumors. It has an association with progression and poor survival of breast cancer. Leptin can regulate endothelial cell proliferation and promote angiogenesis. There are several other factors such as insulin and HER2 may be involved in the relationship between leptin and breast cancer. Leptin system has emerged as a new and promising therapeutic target for breast cancer. This review article summarizes the current knowledge about the relation of leptin and breast cancer.en_US
dc.identifier.doi10.1007/s12032-011-0056-0en_US
dc.identifier.endpage1514en_US
dc.identifier.issn1357-0560en_US
dc.identifier.issn1559-131Xen_US
dc.identifier.issue3en_US
dc.identifier.pmid21877194en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1510en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s12032-011-0056-0
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28193
dc.identifier.volume29en_US
dc.identifier.wosWOS:000307964100016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHUMANA PRESS INCen_US
dc.relation.ispartofMEDICAL ONCOLOGYen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectBreast canceren_US
dc.subjectLeptinen_US
dc.subjectTreatmenten_US
dc.subjectPrognosisen_US
dc.titleLeptin and breast cancer: an overviewen_US
dc.typeReviewen_US

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