Comparison of central corneal thickness measurements using optical low-coherence reflectometry, Fourier domain optical coherence tomography, and Scheimpflug camera

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dc.contributor.authorGonul, Saban
dc.contributor.authorKoktekir, Bengu Ekinci
dc.contributor.authorBakbak, Berker
dc.contributor.authorGedik, Sansal
dc.date.accessioned2020-03-26T18:49:48Z
dc.date.available2020-03-26T18:49:48Z
dc.date.issued2014
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: To compare the results of central corneal thickness (CCT) measurements obtained using optical low-coherence reflectometry (OLCR), Fourier domain optical coherence tomography (FD-OCT), and a Scheimpflug camera (SC), combined with Placido corneal topography. Methods: A total of 25 healthy subjects were enrolled in the present study, and one eye of each subject was included. A detailed ophthalmic examination was performed in all cases following CCT measurements with OLCR, FD-OCT, and SC. The results were compared using an ANOVA test. Bland-Altman analysis was used to demonstrate agreement between methods. Intra-examiner repeatability was assessed by using intraclass correlation coefficients (ICCs). Results: Statistically significant differences were observed between the results of the CCT measurements obtained using the three different devices (p=0.009). Significant correlations were found between OLCR and FD-OCT (r=0.97; p<0.0001), FD-OCT and SC (r=0.91; p<0.0001), and OLCR and SC (r=0.95; p<0.0001). The 95% limits of agreement (LOA) obtained from Bland-Altman plots were from -7.2 mu m to 28.7 mu m for OLCR versus FD-OCT, from -19.2 mu m to 30.4 mu m for OLCR versus SC, and from -42.6 to 32.3 mu m for FD-OCT versus SC. Intra-examiner repeatability was excellent for each method, with ICCs >0.98. Conclusions: Although the results of CCT measurements obtained from these three devices were highly correlated with one another and the mean differences between instruments were comparable with the reported diurnal CCT fluctuation, the measurements are not directly interchangeable in clinical practice because of the wide LOA values.en_US
dc.identifier.doi10.5935/0004-2749.20140087en_US
dc.identifier.endpage350en_US
dc.identifier.issn0004-2749en_US
dc.identifier.issn1678-2925en_US
dc.identifier.issue6en_US
dc.identifier.pmid25627178en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage345en_US
dc.identifier.urihttps://dx.doi.org/10.5935/0004-2749.20140087
dc.identifier.urihttps://hdl.handle.net/20.500.12395/30689
dc.identifier.volume77en_US
dc.identifier.wosWOS:000348589700002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCONSEL BRASIL OFTALMOLOGIAen_US
dc.relation.ispartofARQUIVOS BRASILEIROS DE OFTALMOLOGIAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCornea/anatomy & histologyen_US
dc.subjectCorneal topography/methodsen_US
dc.subjectTomography, optical coherence/methodsen_US
dc.subjectFourier analysisen_US
dc.subjectComparative studyen_US
dc.subjectObserver variationen_US
dc.titleComparison of central corneal thickness measurements using optical low-coherence reflectometry, Fourier domain optical coherence tomography, and Scheimpflug cameraen_US
dc.typeArticleen_US

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