CD4+ T Cell/CD8+ T Cell Ratio in the Anterior Chamber of the Eye After Penetrating Injury and Its Comparison with Normal Aqueous Samples

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dc.contributor.authorAvunduk, Avni Murat
dc.contributor.authorAvunduk, Mustafa Cihat
dc.contributor.authorTekelioğlu, Yavuz
dc.contributor.authorKapıcıoğlu, Zerrin
dc.date.accessioned2020-03-26T16:26:05Z
dc.date.available2020-03-26T16:26:05Z
dc.date.issued1998
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractWe have recently reported that significantly more CD8(+) T-cell activity is present in the aqueous humor compared to peripheral blood. The aim of the current study is to investigate the effect of the ocular trauma on the number of the T lymphocyte subsets in the aqueous humor. CD4(+)/CD8(+) T-cell ratios in the aqueous and blood samples of 12 patients who suffered from traumatic iridocyclitis because of a corneal perforation were compared to those of patients with senile cataracts. We found a relatively higher CD4(+)/CD8(+) cell ratio in the aqueous samples of traumatized patients than cataractous patients. Meanwhile, no difference was present between the aqueous and blood samples of the traumatized patients with respect to the above-mentioned ratio. We suggest that one of the most important factors in maintaining a lower CD4(+)/CD8(+) cell ratio in normal aqueous humor compared to peripheral blood is an intact blood-aqueous barrier. Blood-aqueous barrier may play a participating role in the pathogenesis of immunosuppressive properties of the anterior chamber of the eye by establishing higher CD8(+) T-cell activity in the aqueous humor relative to the peripheral blood.en_US
dc.identifier.citationAvunduk, M. C., Avunduk, A. M., Tekelioğlu, Y., Kapıcıoğlu, Z., (1998). CD4+ T Cell/CD8+ T Cell Ratio in the Anterior Chamber of the Eye After Penetrating Injury and Its Comparison with Normal Aqueous Samples. Japanese Journal of Ophthalmology, 42(3), 204-207. Doi:10.1016/S0021-5155(97)00142-1
dc.identifier.doi10.1016/S0021-5155(97)00142-1en_US
dc.identifier.endpage207en_US
dc.identifier.issn0021-5155en_US
dc.identifier.issue3en_US
dc.identifier.pmid9690899en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage204en_US
dc.identifier.urihttps://dx.doi.org/10.1016/S0021-5155(97)00142-1
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16749
dc.identifier.volume42en_US
dc.identifier.wosWOS:000073772400009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAvunduk, Mustafa Cihat
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE INCen_US
dc.relation.ispartofJapanese Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAnterior Chamber-Associated Immune Deviationen_US
dc.subjectAqueous Humoren_US
dc.subjectCD4(+) T Cellen_US
dc.subjectCD8(+) T Cellen_US
dc.subjectHumanen_US
dc.subjectImmunologyen_US
dc.subjectTraumatic Iridocyclitisen_US
dc.titleCD4+ T Cell/CD8+ T Cell Ratio in the Anterior Chamber of the Eye After Penetrating Injury and Its Comparison with Normal Aqueous Samplesen_US
dc.typeArticleen_US

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