Successful Treatment of Suicide Attempt by Megadose of Propafenone and Captopril

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dc.contributor.authorAvci, Ahmet
dc.contributor.authorYilmaz, Ahmet
dc.contributor.authorCelik, Mustafa
dc.contributor.authorDemir, Kenan
dc.contributor.authorKeles, Fikret
dc.date.accessioned2020-03-26T18:43:33Z
dc.date.available2020-03-26T18:43:33Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIntoxication caused by propafenone is very rare, and there is no case reported before propafenone and captopril intoxication together. There are few case reports in the literature about intoxication with more than 6 g of propafenone. We present the clinical manifestation and successfully treatment of 9 g of propafenone and 1 g captopril intoxication in an 18-year-old female. An 18-year-old female was brought to the emergency department approximately half an hour after she committed suicide with 30 propafenone tablets, 300 mg each, and 20 captopril tablets, 50 mg each. Her fist electrocardiography (ECG) shows a chaotic ventricular rhythm with a prolonged QRS complex. After fluid and sodium bicarbonate infusion and permanent pacemaker implantation, sinus rhythm was achieved. This case, to our knowledge, is the first in that it describes the successful recovery of a patient who ingested extensively large doses of propafenone (9 g) and captopril (1 g), both of which are known to have severe cardiac side effects.en_US
dc.identifier.doi10.1007/s12012-013-9201-7en_US
dc.identifier.endpage233en_US
dc.identifier.issn1530-7905en_US
dc.identifier.issue3en_US
dc.identifier.pmid23397376en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage230en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s12012-013-9201-7
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29848
dc.identifier.volume13en_US
dc.identifier.wosWOS:000324110000005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHUMANA PRESS INCen_US
dc.relation.ispartofCARDIOVASCULAR TOXICOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectPropafenoneen_US
dc.subjectCaptoprilen_US
dc.subjectPoisoningen_US
dc.subjectSuicide attempten_US
dc.titleSuccessful Treatment of Suicide Attempt by Megadose of Propafenone and Captoprilen_US
dc.typeArticleen_US

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