The usefulness of plasma asymmetric dimethylarginine (ADMA) levels and tissue doppler echocardiography for heart function in term infants born to mothers with gestational diabetes mellitus

Basit Öğe Kaydı
dc.contributor.authorArslan, Derya
dc.contributor.authorOran, Bulent
dc.contributor.authorVatansev, Husamettin
dc.contributor.authorCimen, Derya
dc.contributor.authorGuvenc, Osman
dc.date.accessioned2020-03-26T18:44:12Z
dc.date.available2020-03-26T18:44:12Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to examine whether asymmetric dimethylarginine (ADMA) concentrations are associated with ventricular function in the infants of mothers with gestational diabetes. Method: Twenty-five term newborns of mothers with gestational diabetes and term newborns as the control group (n=25) with normal general health status were evaluated at two time points, on the 3rd postnatal day, at the 3th months. Echocardiographic evaluations of all participants were performed and ADMA level was measured. Results: In the first analysis, 10 patients (40%) had a septal thickness of 6mm or more, indicating septal hypertrophy. In the first and second analysis, interventricular septum end-diastolic thickness (IVSTd) and the left ventricular posterior wall end-diastolic thickness (LVPWTd) in the patient group were higher than the control group. ADMA level measurement was not significantly different between the groups the first and second analysis. There was no difference in ADMA levels of the group with septal thickness >= 6mm and the group with <6 mm. Conclusion: Newborn cardiac wall thickness was increased in pregnancies complicated by Gestational diabetes mellitus (GDM), and the increase was independent of glycemic control. Diastolic newborn cardiac function was impaired in GDM, and this effect was independent of septal thickness. We found no association between ADMA levels and cardiac systolic, diastolic functions or septum thickness in the GDM newborn.en_US
dc.identifier.doi10.3109/14767058.2013.798288en_US
dc.identifier.endpage1748en_US
dc.identifier.issn1476-7058en_US
dc.identifier.issn1476-4954en_US
dc.identifier.issue17en_US
dc.identifier.pmid23614659en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1742en_US
dc.identifier.urihttps://dx.doi.org/10.3109/14767058.2013.798288
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29958
dc.identifier.volume26en_US
dc.identifier.wosWOS:000325989000015en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofJOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAsymmetric dimethylarginineen_US
dc.subjectgestational diabetesen_US
dc.subjectnewbornen_US
dc.subjecttissue Doppler imagingen_US
dc.titleThe usefulness of plasma asymmetric dimethylarginine (ADMA) levels and tissue doppler echocardiography for heart function in term infants born to mothers with gestational diabetes mellitusen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu