A comparison of the effects on postoperative bleeding of the intra-articular application of tranexamic acid and adrenalin in total knee arthroplasty

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dc.contributor.authorDurgut, Fatih
dc.contributor.authorErkocak, Omer Faruk
dc.contributor.authorAydin, Bahattin Kerem
dc.contributor.authorOzdemir, Ali
dc.contributor.authorGulec, Ali
dc.contributor.authorTugrul, Ali Ihsan
dc.date.accessioned2020-03-26T20:12:17Z
dc.date.available2020-03-26T20:12:17Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: To compare the efficacies of intra-articular applications of tranexamic acid and adrenaline on postoperative bleeding after total knee arthroplasty. Methods: The single-center, retrospective, controlled study was conducted at Selcuk University, department of orthopedics surgery and comprised data of patients who underwent primary, unilateral, cemented total knee arthroplasty between July 2012 and December 2014. Group 1 had received tranexamic acid 1g after closure of articular capsule. Group 2 had received adrenalin. Group 3, the control group, received no medication intra-articularly after total knee arthroplasty. The amount of blood collected in the drain and postoperative alterations in haemoglobin and haematocrit values were compared. Results: Of the total 90 subjects, there were 30(33.33%) in each of the three groups. The decrease of haemoglobin and haematocrit values in Group 1 was statistically significant compared to both Group 2 and Group 3 (p<0.05). The amount of blood collected in the drains was remarkably lower in Groups I and 2 compared to Group III (p<0.05). No deep venous thrombosis or pulmonary emboli were encountered across the sample. Conclusion: Intra-articular administration of tranexamic acid was found to be beneficial and safe for the achievement of effective haemostasis after total knee arthroplasty.en_US
dc.identifier.endpage329en_US
dc.identifier.issn0030-9982en_US
dc.identifier.issue3en_US
dc.identifier.pmid30890822en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage325en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37404
dc.identifier.volume69en_US
dc.identifier.wosWOS:000462780600004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPAKISTAN MEDICAL ASSOCen_US
dc.relation.ispartofJOURNAL OF THE PAKISTAN MEDICAL ASSOCIATIONen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectTranexamic aciden_US
dc.subjectAdrenalineen_US
dc.subjectHaemostasisen_US
dc.subjectBlood lossen_US
dc.subjectTotal knee arthroplastyen_US
dc.titleA comparison of the effects on postoperative bleeding of the intra-articular application of tranexamic acid and adrenalin in total knee arthroplastyen_US
dc.typeArticleen_US

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