Oral squamous cell carcinoma with lymph node metastasis in a 12 years-old sphynx female cat
Küçük Resim Yok
Dosyalar
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Selçuk Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu raporda, 12 yaşında Sfenks ırkı dişi bir kedide lenf nodu metastazı olan oral yassı hücreli karsinom (OYHK) olgusu tanımlanmıştır. Mandibular lenf nodu tamamen çıkarıldı ve diseke edildi (lenfadenektomi). Ağız mukozasındaki nekrotik-ülserli kitle ekstirpe edildi. Oral kitlede, atipik hücresel özelliklere sahip pleomorfik yassı epitel hücreleri, erozyonlar ve ülserler de gözlendi. Mandibular lenf nodunda belirgin atipik hücre özelliklerine sahip yassı epitel hücreleri bulundu. İmmunohistokimyasal incelemede neoplastik hücrelerin AE1-AE3 ve sitokeratin 5/6 için pozitif olduğu görüldü. Ağız mukozasında erozyon ve ülserlerle seyreden kronik gingivostomatitisli köpek ve kedilerin OYHK açısından da değerlendirilmesi gerektiğine dikkat çekmek amacıyla olgunun sunulması uygun bulunmuştur
In this report, a case of oral squamous cell carcinoma (OSCC) with lymph node metastasis was described in a 12 years-old Sphynx female cat. The mandibular lymph node was totally removed and dissected (lymphadenectomy). The oral necrotic-ulcerated mass was extirpated. In the oral mass, pleomorphic squamous epithelial cells with atypical cellular features, erosions and ulcers were also observed. Squamous epithelial cells with prominent atypical cell features were found in the mandibular lymph node. Immunohistochemical examination revealed that neoplastic cells were positive for AE1-AE3 and cytokeratin 5/6. It was found appropriate to present the case in order to draw attention to the fact that dogs and cats with chronic gingivostomatitis with erosions and ulcers on the oral mucosa should also be evaluated in terms of OSCC.
In this report, a case of oral squamous cell carcinoma (OSCC) with lymph node metastasis was described in a 12 years-old Sphynx female cat. The mandibular lymph node was totally removed and dissected (lymphadenectomy). The oral necrotic-ulcerated mass was extirpated. In the oral mass, pleomorphic squamous epithelial cells with atypical cellular features, erosions and ulcers were also observed. Squamous epithelial cells with prominent atypical cell features were found in the mandibular lymph node. Immunohistochemical examination revealed that neoplastic cells were positive for AE1-AE3 and cytokeratin 5/6. It was found appropriate to present the case in order to draw attention to the fact that dogs and cats with chronic gingivostomatitis with erosions and ulcers on the oral mucosa should also be evaluated in terms of OSCC.
Açıklama
Anahtar Kelimeler
Kedi, Metastaz, Oral Yassı Hücreli Karsinom, Sfenks, Cat, Metastasis, Oral Squamous Cell Carcinoma, Sphynx
Kaynak
Eurasian Journal of Veterinary Sciences
WoS Q Değeri
Scopus Q Değeri
Cilt
40
Sayı
3
Künye
Hatipoglu F, Tas A, Bozkurt MF, Risvanli A et al 2024. Oral Squamous Cell Carcinoma with Lymph Node Metastasis in a 12 Years-Old Sphynx Female Cat Eurasian J Vet Sci, 40, 3, 131-136. 10.15312/EurasianJVetSci.2024.437
