The prognostic value of the Glasgow coma scale, serum acetylcholinesterase and leukocyte levels in acute organophosphorus poisoning

Basit Öğe Kaydı
dc.contributor.authorCander, Basar
dc.contributor.authorDur, Ali
dc.contributor.authorYildiz, Mesut
dc.contributor.authorKoyuncu, Feridun
dc.contributor.authorGirisgin, Abdullah Sadik
dc.contributor.authorGul, Mehmet
dc.contributor.authorOkumus, Mehmet
dc.date.accessioned2020-03-26T18:17:07Z
dc.date.available2020-03-26T18:17:07Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBACKGROUND AND OBJECTIVES: Organophosphate poisoning (OP) is a serious clinical condition that may sometimes be fatal. The aim of this study was to determine whether the Glasgow coma scale (GCS), and serum acetylcholinesterase and leukocyte levels have prognostic value in acute OP poisoning. DESIGN AND SETTING: Retrospective review of records of patients admitted to the intensive care unit of Selcuk University, Meram Medical Faculty, Emergency Department, Konya, Turkey, between January 2006 and January 2009. METHODS: We studied acutely OP-poisoned patients admitted within 24 hours after OP exposure. RESULTS: The mean age of the 25 patients was 37 years (range, 20-80 years). Three (12%) of the 25 patients (male-female ratio, 12: 13) died. The mean GCS values of the patients who died were significantly lower compared to those of the group that survived (4 vs 11.7, respectively P <.05). While the mean serum acetylcholinesterase levels were lower in the patients who died, the difference in the mean serum acetylcholinesterase levels between the patients who died and the ones who survived was not statistically significant (3841 IU/L vs. 1768 IU/L, respectively). CONCLUSION: Although serum cholinesterase values can be used in the quick diagnosis, their efficiency at predicting outcome in patients with OP poisoning has not been established. It has also been determined that serum leukocyte values have no prognostic value in OP poisoning, but GCS values have been found to be effective in predicting the outcome.en_US
dc.identifier.doi10.4103/0256-4947.78203en_US
dc.identifier.endpage166en_US
dc.identifier.issn0256-4947en_US
dc.identifier.issue2en_US
dc.identifier.pmid21422653en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage163en_US
dc.identifier.urihttps://dx.doi.org/10.4103/0256-4947.78203
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26980
dc.identifier.volume31en_US
dc.identifier.wosWOS:000288809700008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherK FAISAL SPEC HOSP RES CENTREen_US
dc.relation.ispartofANNALS OF SAUDI MEDICINEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleThe prognostic value of the Glasgow coma scale, serum acetylcholinesterase and leukocyte levels in acute organophosphorus poisoningen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu