Effects of exposure to 2100 MHz GSM-like radiofrequency electromagnetic field on auditory system of rats

Basit Öğe Kaydı
dc.contributor.authorCeliker, Metin
dc.contributor.authorOzgur, Abdulkadir
dc.contributor.authorTumkaya, Levent
dc.contributor.authorTerzi, Suat
dc.contributor.authorYilmaz, Mustafa
dc.contributor.authorKalkan, Yildiray
dc.contributor.authorErdogan, Ender
dc.date.accessioned2020-03-26T19:35:22Z
dc.date.available2020-03-26T19:35:22Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIntroduction: The use of mobile phones has become widespread in recent years. Although beneficial from the communication viewpoint, the electromagnetic fields generated by mobile phones may cause unwanted biological changes in the human body. Objective: In this study, we aimed to evaluate the effects of 2100 MHz Global System for Mobile communication (GSM-like) electromagnetic field, generated by an electromagnetic fields generator, on the auditory system of rats by using electrophysiological, histopathologic and immunohistochemical methods. Methods: Fourteen adult Wistar albino rats were included in the study. The rats were divided randomly into two groups of seven rats each. The study group was exposed continuously for 30 days to a 2100 MHz electromagnetic fields with a signal level (power) of 5.4 dBm (3.47 mW) to simulate the talk mode on a mobile phone. The control group was not exposed to the aforementioned electromagnetic fields. After 30 days, the Auditory Brainstem Responses of both groups were recorded and the rats were sacrificed. The cochlear nuclei were evaluated by histopathologic and immunohistochemical methods. Results: The Auditory Brainstem Responses records of the two groups did not differ significantly. The histopathologic analysis showed increased degeneration signs in the study group (p = 0.007). In addition, immunohistochemical analysis revealed increased apoptotic index in the study group compared to that in the control group (p = 0.002). Conclusion: The results support that long-term exposure to a GSM-like 2100 MHz electromagnetic fields causes an increase in neuronal degeneration and apoptosis in the auditory system. (C) 2016 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial. Published by Elsevier Editora Ltda.en_US
dc.identifier.doi10.1016/j.bjorl.2016.10.004en_US
dc.identifier.endpage696en_US
dc.identifier.issn1808-8694en_US
dc.identifier.issn1808-8686en_US
dc.identifier.issue6en_US
dc.identifier.pmid27865708en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage691en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.bjorl.2016.10.004
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35041
dc.identifier.volume83en_US
dc.identifier.wosWOS:000417392200014en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherASSOC BRASILEIRA OTORRINOLARINGOLOGIA & CIRURGIA CERVICOFACIALen_US
dc.relation.ispartofBRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCochlear nucleien_US
dc.subjectNeuronal degenerationen_US
dc.subjectElectromagnetic radiationen_US
dc.titleEffects of exposure to 2100 MHz GSM-like radiofrequency electromagnetic field on auditory system of ratsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu