Investigation of histopathologic changes in the ureter walls in vesicoureteral reflux

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dc.contributor.authorYurtcu, Mueslim
dc.contributor.authorGurbuzer, Nilifer
dc.contributor.authorFindik, Siddika
dc.contributor.authorAvunduk, Mustafa Cihat
dc.contributor.authorGunel, Engin
dc.date.accessioned2020-03-26T17:39:01Z
dc.date.available2020-03-26T17:39:01Z
dc.date.issued2009
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: This study aimed to determine the histopathologic changes in ureteral walls (UWs) in children with vesicoureteral reflux (VUR). Methods: Twenty ureteral specimens taken from children were divided into 2 groups, refluxing (R) and control (C) groups, each containing 10 specimens. Wall thickness of the ureter, tunica muscularis of the ureter, mucosal thickness of the ureter (uroepithelium), collagen thickness of the ureter, mucosal change, and inflammation were evaluated in resected distal UWs in children with VUR. Results: The mean wall thickness of the ureter, mean tunica muscularis of the ureter, and mean uroepithelium values of the UWs in the R group were not significantly lower compared to those in the C group. Collagen thickness values in the R group were significantly lower than those in the C group. Conclusions: Our data suggest that wall thickness (tunica muscularis and uroepithelium) was not significantly decreased, but collagen thickness of the ureter was decreased in the UWs of children with VUR. (C) 2009 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.jpedsurg.2008.08.018en_US
dc.identifier.endpage805en_US
dc.identifier.issn0022-3468en_US
dc.identifier.issn1531-5037en_US
dc.identifier.issue4en_US
dc.identifier.pmid19361644en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage802en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.jpedsurg.2008.08.018
dc.identifier.urihttps://hdl.handle.net/20.500.12395/23626
dc.identifier.volume44en_US
dc.identifier.wosWOS:000265467100021en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B SAUNDERS CO-ELSEVIER INCen_US
dc.relation.ispartofJOURNAL OF PEDIATRIC SURGERYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectUreteral wallen_US
dc.subjectVesicoureteral refluxen_US
dc.subjectTunica muscularisen_US
dc.subjectUroepitheliumen_US
dc.subjectCollagenen_US
dc.titleInvestigation of histopathologic changes in the ureter walls in vesicoureteral refluxen_US
dc.typeArticleen_US

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