Relationship between neutrophil functions and severity of periodontitis in obese and/or type 2 diabetic chronic periodontitis patients

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dc.contributor.authorGursoy, Ulvi Kahraman
dc.contributor.authorMarakoglu, Ismail
dc.contributor.authorOztop, A. Yasemin
dc.date.accessioned2020-03-26T17:27:37Z
dc.date.available2020-03-26T17:27:37Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectives: Obesity and diabetes are the most common nutritional and endocrine disorders in developed and developing countries and are related to immune response alterations. Recent studies suggest an association among diabetes, obesity, and periodontitis. The aim of this study was to evaluate the relationship between neutrophil function alterations and periodontal disease severity of type 2 diabetic chronic periodontitis patients with and without obesity. Method and Materials: A total of 39 chronic periodontitis patients participated in the study. The study population was divided into 4 groups according to body mass index and type 2 diabetes status: (1) 8 type 2 diabetic obese patients, (2) 12 type 2 diabetic patients, (3) 8 obese patients, and (4) 11 systemically healthy patients as a control group. Neutrophil chemotaxis and phagocytosis functions and periodontal status were evaluated. Results: No differences in age, Gingival Index, Plaque Index, percentage of phagocytosis, phagocytic efficiency, and intracellular killing were observed among the groups, but chemotaxis was significantly lower in diabetic groups than the control group and probing depth was significantly higher in diabetic groups than the control group. Obesity did not seem to affect the results significantly for all parameters evaluated. Conclusions: Unlike in patients with type 2 diabetes, neither neutrophil functions nor periodontitis severity seemed to change in obese patients. However, in type 2 diabetic patients, neutrophil chemotaxis alterations seem to affect probing depth measurements.en_US
dc.identifier.endpage489en_US
dc.identifier.issn0033-6572en_US
dc.identifier.issue6en_US
dc.identifier.pmid19057744en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage485en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22606
dc.identifier.volume39en_US
dc.identifier.wosWOS:000257892700004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherQUINTESSENCE PUBLISHING CO INCen_US
dc.relation.ispartofQUINTESSENCE INTERNATIONALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectneutrophil functionsen_US
dc.subjectobesityen_US
dc.subjectperiodontitis severityen_US
dc.subjecttype 2 diabetes mellitusen_US
dc.titleRelationship between neutrophil functions and severity of periodontitis in obese and/or type 2 diabetic chronic periodontitis patientsen_US
dc.typeArticleen_US

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