Static Magnetic Field Inhibits Adenosine Deaminase Activity in Cancerous and Noncancerous Human Gastric Tissues

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dc.contributor.authorDurak, Zahide Esra
dc.contributor.authorKocaoglu, Ender Hilmi
dc.contributor.authorOzturk, Bahadir
dc.date.accessioned2020-03-26T18:58:31Z
dc.date.available2020-03-26T18:58:31Z
dc.date.issued2014
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAim: Investigation of possible effects of static magnetic field (SMF) on adenosine deaminase (ADA) activity in cancerous and noncancerous human gastric and colon tissues to obtain information about possible action mechanism of SMF. Materials and Methods: Cancerous and noncancerous human gastric and colon tissues removed from patients by surgical operations were used in the studies. SMF was created by using two static magnets. Before and after treatment with SMF, ADA activities in the tissue samples were measured. Results: The ADA activity was found to be lowered in gastric tissues treated with the SMF. However, no change was observed in the ADA activity of colon tissues. Conclusions: Our results suggest that SMF inhibits the ADA enzyme in gastric tissues significantly. It is supposed that, in addition to other proposed mechanisms, accumulated adenosine due to the inhibition of the ADA enzyme might also play a part in the anticancer activity of SMF.en_US
dc.identifier.doi10.1089/cbr.2013.1585en_US
dc.identifier.endpage165en_US
dc.identifier.issn1084-9785en_US
dc.identifier.issn1557-8852en_US
dc.identifier.issue4en_US
dc.identifier.pmid24784458en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage162en_US
dc.identifier.urihttps://dx.doi.org/10.1089/cbr.2013.1585
dc.identifier.urihttps://hdl.handle.net/20.500.12395/31149
dc.identifier.volume29en_US
dc.identifier.wosWOS:000336535800003en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMARY ANN LIEBERT, INCen_US
dc.relation.ispartofCANCER BIOTHERAPY AND RADIOPHARMACEUTICALSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectadenosine deaminaseen_US
dc.subjectcanceren_US
dc.subjectstatic magnetic fielden_US
dc.titleStatic Magnetic Field Inhibits Adenosine Deaminase Activity in Cancerous and Noncancerous Human Gastric Tissuesen_US
dc.typeArticleen_US

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