The Effect of Smoking on Myocardial Performance Index in Middle-Aged Males after First Acute Myocardial Infarction

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dc.contributor.authorBacaksiz, Ahmet
dc.contributor.authorKayrak, Mehmet
dc.contributor.authorVatankulu, Mehmet Akif
dc.contributor.authorAyhan, Selim S.
dc.contributor.authorSonmez, Osman
dc.contributor.authorAkilli, Hakan
dc.contributor.authorAribas, Alpay
dc.date.accessioned2020-03-26T18:43:56Z
dc.date.available2020-03-26T18:43:56Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: Cigarette smoking is associated with increased rates of coronary artery disease and acute myocardial infarction (MI). Paradoxically, smokers had lower mortality after MI. The purpose of this study was to evaluate the effect of chronic smoking on myocardial performance index (MPI) in middle-aged men after an acute MI. Material and methods: A total of 429 patients (325 smokers vs. 104 nonsmokers) presenting with acute ST elevation MI were enrolled in this study. Thrombolysis in myocardial infarction (TIMI) flow of the infarct related artery was measured before and after the primary percutaneous coronary intervention (PCI), and Gensini score was also calculated. Conventional echocardiography and tissue Doppler echocardiography (TDI) were performed within 4872hours after onset of chest pain. Peak early (Em) and late (Am) diastolic velocities, peak systolic (Sm) mitral annular velocities and time intervals were recorded with TDI. The MPI, ratio of Em/Am, and E/Em were calculated. Results: Baseline demographic and angiographic characteristics such as Gensini score, pre and, post PCI TIMI flow were similar in 2 groups. In contrast, LV MPI was preserved among smokers (0.59 +/- 0.15 vs. 0.66 +/- 0.14, P=0.01), and Em/Am values were also higher in smokers (0.84 +/- 0.28 vs. 0.75 +/- 0.31, P=0.01). Independent predictors of impaired MPI (0.60) were determined as nonsmoking status (odds ratio 2.940, 95% CI 0.985.83, P=0.05), left anterior descending artery stenosis (odds ratio 3.196, 95% CI 1.735.91 P=0.001), and, age (odds ratio 1.12, 95% CI 1.031.22, P=0.01). Conclusions: Despite similar demographic and angiographic characteristics, smoker males had a paradoxically better MPI after acute MI.en_US
dc.identifier.doi10.1111/echo.12029en_US
dc.identifier.endpage163en_US
dc.identifier.issn0742-2822en_US
dc.identifier.issn1540-8175en_US
dc.identifier.issue2en_US
dc.identifier.pmid23167610en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage155en_US
dc.identifier.urihttps://dx.doi.org/10.1111/echo.12029
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29915
dc.identifier.volume30en_US
dc.identifier.wosWOS:000314920100016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectsmokingen_US
dc.subjectTei indexen_US
dc.subjectacute myocardial infarctionen_US
dc.subjecttissue Doppler echocardiographyen_US
dc.titleThe Effect of Smoking on Myocardial Performance Index in Middle-Aged Males after First Acute Myocardial Infarctionen_US
dc.typeArticleen_US

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