Acetylcholinesterase inhibitory and antioxidant properties of Cyclotrichium niveum, Thymus praecox subsp caucasicus var. caucasicus, Echinacea purpurea and E. pallida

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dc.contributor.authorOrhan, I.
dc.contributor.authorSenol, F. S.
dc.contributor.authorGuelpinar, A. R.
dc.contributor.authorKartal, M.
dc.contributor.authorSekeroglu, N.
dc.contributor.authorDeveci, M.
dc.contributor.authorKan, Y.
dc.date.accessioned2020-03-26T17:37:48Z
dc.date.available2020-03-26T17:37:48Z
dc.date.issued2009
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe dichloromethane, ethyl acetate, ethanol, and aqueous extracts of Cyclotrichium niveum (CN) and Thymus praecox subsp. caucasicus var. caucasicus (TP), Echinacea purpurea (EPU), and E pallida (EPA) along with the essential oils of CN and TP were assessed for their anti-acetylcholinesterase (AChE) and antioxidant activities. AChE inhibition was estimated using spectrophotometric method of Ellman. Antioxidant activity was evaluated by 2,2-diphenyl-2-picrylhydrazyl(DPPH) radical scavenging and ferrous ion-chelating power tests. Ferric-reducing antioxidant power (FRAP) of CN and TP were also tested. CN essential oil was found to contain isomenthone (56.21%) and pulegone (19.76%). The ethyl acetate (83.11-87.98%) and dichloromethane (73.45-84.02%) extracts of CN showed the highest AChE inhibition. The ethyl acetate and ethanol extracts of TP exerted significant DPPH scavenger effect. The water extracts of CN and TP and the chloroform extract of the aerial parts of EPU displayed the highest ferrous ion-chelating effect. The leaf and flower essential oils of TP had the best FRAP. (C) 2009 Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipTurkish Scientific and Technical Research Council (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK)en_US
dc.description.sponsorshipOne of the authors (F. Sezer Senol) would like to acknowledge the scholarship for master program provided by the Turkish Scientific and Technical Research Council (TUBITAK).en_US
dc.identifier.doi10.1016/j.fct.2009.03.004en_US
dc.identifier.endpage1310en_US
dc.identifier.issn0278-6915en_US
dc.identifier.issn1873-6351en_US
dc.identifier.issue6en_US
dc.identifier.pmid19285534en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1304en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.fct.2009.03.004
dc.identifier.urihttps://hdl.handle.net/20.500.12395/23248
dc.identifier.volume47en_US
dc.identifier.wosWOS:000266418300037en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPERGAMON-ELSEVIER SCIENCE LTDen_US
dc.relation.ispartofFOOD AND CHEMICAL TOXICOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCyclotrichium niveumen_US
dc.subjectThymus praecox subsp caucasicus var. caucasicusen_US
dc.subjectEchinaceaen_US
dc.subjectEssential oilen_US
dc.subjectAcetylcholinesterase inhibitionen_US
dc.subjectAntioxidant activityen_US
dc.titleAcetylcholinesterase inhibitory and antioxidant properties of Cyclotrichium niveum, Thymus praecox subsp caucasicus var. caucasicus, Echinacea purpurea and E. pallidaen_US
dc.typeArticleen_US

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