The protective efficacy of immunoglobulin Y from immunized chickens against Salmonella infections in mice

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dc.contributor.authorHadimli, Hasan Huseyin
dc.contributor.authorSayin, Zafer
dc.contributor.authorSanioglu Golen, Gokcenur
dc.date.accessioned2020-03-26T19:43:06Z
dc.date.available2020-03-26T19:43:06Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of this study was to determine the efficacy of immunoglobulin Y (IgY) obtained from chickens immunized with Salmonella vaccines. Chickens were vaccinated three times with inactivated monovalent, bivalent, and combined vaccines. Immunized hen eggs were collected after the third vaccination and IgYs were purified. In total, 100 mice were orally challenged with Salmonella serotypes. After the challenge, IgYs were orally administered to mice. Mice were observed for morbidity and mortality. Fecal samples from the mice were also cultured for the reisolation of Salmonella serotypes. The antibody titers in the serum samples of vaccinated chickens were higher than those of controls (P < 0.001). Neither morbidity nor mortality were observed in these mice. In all of the groups the reisolation numbers of the Salmonella serotypes from internal organs and fecal samples were low ( P < 0.001) In conclusion, it is suggested that IgYs from immunized chickens could be used to establish protection against Salmonella infections.en_US
dc.description.sponsorshipTUBITAK-TOVAGTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [112O324]en_US
dc.description.sponsorshipThis study is part of a project supported by TUBITAK-TOVAG (Project No: 112O324). The abstract was presented as a poster at the 9th World Congress on Alternatives and Animal Use in the Life Sciences, 24-28 August 2014, Prague, Czech Republic. This research was approved by the Ethics Committee of the Faculty of Veterinary Medicine, Selcuk University, Konya, Turkey (Ethical Committee No: 2012/008).en_US
dc.identifier.doi10.3906/vet-1611-65en_US
dc.identifier.endpage555en_US
dc.identifier.issn1300-0128en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage548en_US
dc.identifier.urihttps://dx.doi.org/10.3906/vet-1611-65
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35599
dc.identifier.volume41en_US
dc.identifier.wosWOS:000409379100013en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherSCIENTIFIC TECHNICAL RESEARCH COUNCIL TURKEY-TUBITAKen_US
dc.relation.ispartofTURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectSalmonellaen_US
dc.subjectprotectionen_US
dc.subjectimmunoglobulin Yen_US
dc.subjectchickenen_US
dc.subjectmiceen_US
dc.titleThe protective efficacy of immunoglobulin Y from immunized chickens against Salmonella infections in miceen_US
dc.typeArticleen_US

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