Effect of moderate alcohol intake on lipid peroxidation in plasma, erythrocyte and leukocyte and on some antioxidant enzymes

Basit Öğe Kaydı
dc.contributor.authorAkkuş, İdris
dc.contributor.authorGültekin, Fatih
dc.contributor.authorAköz, Mehmet
dc.contributor.authorÇağlayan, Osman
dc.contributor.authorBahçacı, Sinan
dc.contributor.authorCan, Ü. Gülsüm
dc.contributor.authorAy, Mahmut
dc.contributor.authorGürel, Ahmet
dc.date.accessioned2020-03-26T16:25:23Z
dc.date.available2020-03-26T16:25:23Z
dc.date.issued1997
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPlasma, erythrocyte and leukocyte lipid peroxidation, erythrocyte superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and plasma gamma-glutamyl transferase (GGT) levels were investigated in 36 healthy non-drinkers aged between 18-55 years (mean 38.7) and 72 alcohol drinkers aged between 20-48 years (mean 35.3) in order tb determine the oxidative effect of alcohol. Erythrocyte lipid peroxidation of the drinkers (measured in terms of MDA) was found to be significantly (P < 0.05) reduced compared to that of controls. However, when Tukey-HSD and F test with ANOVA were performed, that significance disappears in those who consume less than 140 g of alcohol per day and persists in those who consume more than 140 g of alcohol per day (P < 0.05). Plasma GGT level was significantly increased compared to that of controls (P < 0.001). Also, there was a significant (P = 0.01) correlation between serum GGT level and the amount of alcohol. There were no significant differences between all the other parameters of both groups. Reduced lipid peroxidation of erythrocytes without any accompanying increase in the activities of antioxidant enzymes shows that another mechanism might be responsible for this finding. This mechanism was thought to be an alteration in lipid composition of erythrocyte membranes. (C) 1997 Elsevier Science B.V.en_US
dc.identifier.doi10.1016/S0009-8981(97)00135-6en_US
dc.identifier.endpage147en_US
dc.identifier.issn0009-8981en_US
dc.identifier.issn1873-3492en_US
dc.identifier.issue2en_US
dc.identifier.pmid9437542en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage141en_US
dc.identifier.urihttps://dx.doi.org/10.1016/S0009-8981(97)00135-6
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16578
dc.identifier.volume266en_US
dc.identifier.wosWOS:000071087700007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.relation.ispartofCLINICA CHIMICA ACTAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectalcoholen_US
dc.subjecterythrocyteen_US
dc.subjectleucocyteen_US
dc.subjectlipid peroxidationen_US
dc.subjectsuperoxide dismutaseen_US
dc.subjectglutathione peroxidaseen_US
dc.subjectgamma-glutamyl transferaseen_US
dc.titleEffect of moderate alcohol intake on lipid peroxidation in plasma, erythrocyte and leukocyte and on some antioxidant enzymesen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
6578.pdf
Boyut:
56.27 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu