The incidence of congenital anomalies associated with cleft palate/cleft lip and palate in neonates in the Konya region, Turkey

Basit Öğe Kaydı
dc.contributor.authorAltunhan, Hüseyin
dc.contributor.authorAnnagür, Ali
dc.contributor.authorKonak, Murat
dc.contributor.authorErtuğrul, Sabahattin
dc.contributor.authorÖrs, Rahmi
dc.contributor.authorKoç, Hasan
dc.date.accessioned2020-03-26T18:31:45Z
dc.date.available2020-03-26T18:31:45Z
dc.date.issued2012
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAdditional congenital anomalies have often been found in patients with orofacial clefts. We wanted to find out the incidence and type of congenital malformations that may accompany cleft palate (CP) and cleft lip and palate (CLP) in babies born in the Konya region. A total of 121 newborn babies with CP or CLP were prospectively included in the study, and all were assessed in detail for congenital anomalies. Of 121 babies, 86(71%) had CLP and 35 (29%) had CP. There was at least one congenital malformation in 80 (66%) of the cases. Additional congenital malformations were seen in 26 (74%) of the 35 with isolated CP, and 54 (63%) in the 86 patients with CLP (p < 0.05). The most common congenital malformation was congenital heart disease, followed by head and neck anomalies. The most common congenital heart disease was atrial septal defect. A serious chromosomal anomaly was found in 18/121 patients with CP or CLP (15%). Of the 80 babies in whom congenital malformations were found, 31 (39%) had dysmorphic features. While 21 (68%) of dysmorphic cases had isolated CP, 10 (32%) had CLP (p < 0.05). The rates of premature delivery, intrauterine growth retardation, and consanguinity between parents were higher in patients with CP or CLP. The neonatal mortality was 20% (n = 24). Our results indicate that at least one congenital anomaly is also present in about two-thirds of newborn babies with CP and CLP, and these anomalies significantly increase their morbidity and mortality. All newborn babies with CP and CLP should be screened for additional congenital anomalies, particularly of the cardiovascular system. (c) 2011 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.bjoms.2011.08.001en_US
dc.identifier.endpage544en_US
dc.identifier.issn0266-4356en_US
dc.identifier.issn1532-1940en_US
dc.identifier.issue6en_US
dc.identifier.pmid21880407en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage541en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.bjoms.2011.08.001
dc.identifier.urihttps://hdl.handle.net/20.500.12395/28530
dc.identifier.volume50en_US
dc.identifier.wosWOS:000308518700013en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCHURCHILL LIVINGSTONEen_US
dc.relation.ispartofBRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectOrofacial cleften_US
dc.subjectCleft palateen_US
dc.subjectCleft lip and palateen_US
dc.subjectCongenital anomalyen_US
dc.subjectNeonateen_US
dc.titleThe incidence of congenital anomalies associated with cleft palate/cleft lip and palate in neonates in the Konya region, Turkeyen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
28530.pdf
Boyut:
144.93 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu