Whole-blood thrombelastography using calcium chloride activation in healthy cats

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dc.contributor.authorCol, Ramazan
dc.contributor.authorMontgomery, Alicia
dc.contributor.authorIazbik, Maria Cristina
dc.contributor.authorDefelice, Ashley
dc.contributor.authorSaavedra, Paulo Vilar
dc.contributor.authorCouto, Guillermo
dc.date.accessioned2020-03-26T18:44:27Z
dc.date.available2020-03-26T18:44:27Z
dc.date.issued2013
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThrombelastography (TEG, Haemoscope Corp., Niles, IL, USA) allows for a global evaluation of the hemostatic system; while conventional coagulation tests typically evaluate only one part of the coagulation system, TEG simultaneously examines the interaction between platelets, clotting factors, the fibrinolytic system, and clot retraction mechanisms. Since its development, TEG has been widely employed in human clinical medicine and research, but has only recently gained popularity in veterinary medicine. The purpose of this study was to establish TEG reference ranges in healthy cats using the citrated native technique. In this study, 31 clinically healthy cats were evaluated. We sampled healthy adult cats based on the absence of clinical signs of illness, normal physical examination findings, a complete blood count, hemostasis profile results, and no previous history of bleeding disorders. The cats had 2 distinct tracings: a "normal" tracing similar to that obtained in other species, and a "high lysis" tracing. The percent of lysis at 60 min (LY60) was significantly higher and the percent of lysis at 60 min after MA is reached (CL60) was significantly lower in the "high lysis" group (P < 0.001 for both). Cats in the "high lysis" group also had a significantly shorter reaction time (P - 0.02). Based on the results, citrated native TEG may provide valuable information on global hemostasis in cats. This technique has a high coefficient of variation for the reaction time, kinetic time, and LY60 parameters, likely due to platelet retraction. It should be useful for detecting hypo-and hypercoagulable states in cats with hemostatic disturbances.en_US
dc.description.sponsorshipTUBITAK BIDEBTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [2219]en_US
dc.description.sponsorshipThis study was supported by TUBITAK BIDEB 2219.en_US
dc.identifier.doi10.3906/vet-1110-45en_US
dc.identifier.endpage75en_US
dc.identifier.issn1300-0128en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage68en_US
dc.identifier.urihttps://dx.doi.org/10.3906/vet-1110-45
dc.identifier.urihttps://hdl.handle.net/20.500.12395/29996
dc.identifier.volume37en_US
dc.identifier.wosWOS:000313947600013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherSCIENTIFIC TECHNICAL RESEARCH COUNCIL TURKEY-TUBITAKen_US
dc.relation.ispartofTURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectThrombelastographyen_US
dc.subjecthemostasisen_US
dc.subjectviscoelasticityen_US
dc.subjectcatsen_US
dc.titleWhole-blood thrombelastography using calcium chloride activation in healthy catsen_US
dc.typeArticleen_US

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