Leukocyte Lipid Peroxidation, Superoxide Dismutase, Glutathione Peroxidase and Serum and Leukocyte Vitamin C Levels of Patients with Type II Diabetes Mellitus
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Date
1996
Journal Title
Journal ISSN
Volume Title
Publisher
ELSEVIER SCIENCE BV
Access Rights
info:eu-repo/semantics/openAccess
Abstract
In the present study, leukocyte lipid peroxidation, superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and serum and leukocyte vitamin C levels of patients with type II diabetes mellitus and healthy controls were investigated. Patients consisted of 53 cases (23 male, 30 female) aged 35-75 years and controls of 34 subjects (15 male, 19 female) aged 34-66 years. Leukocyte lipid peroxidation of diabetics was significantly increased (P < 0.05) whereas vitamin C level was decreased (P < 0.05) compared to those of controls. There was no significant difference in the other parameters. Also, there was no correlation between the above parameters and HbA(1)c and glucose levels. Our results show that leukocytes of diabetics are affected by oxidative stress which might be a reason for decreased microbicidal activity.
Description
Keywords
diabetes mellitus, leukocyte lipid peroxidation, superoxide dismutase, glutathione peroxidase, vitamin C
Journal or Series
Clinica Chimica Acta
WoS Q Value
N/A
Scopus Q Value
Q1
Volume
244
Issue
2
Citation
Akkuş, İ., Kalak, S., Vural, H., Çağlayan, O., Menekşe, E., Can, G., Durmuş, B., (1996). Leukocyte Lipid Peroxidation, Superoxide Dismutase, Glutathione Peroxidase and Serum and Leukocyte Vitamin C Levels of Patients with Type II Diabetes Mellitus. Clinica Chimica Acta, 244(2), 221-227.
