Evaluation of the biocompatibility and osteoproductive activity of ostrich eggshell powder in experimentally induced calvarial defects in rabbits

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dc.contributor.authorDurmus, Ercan
dc.contributor.authorCelik, Ilhami
dc.contributor.authorAydin, M. Faruk
dc.contributor.authorYildirim, Guelsuen
dc.contributor.authorSur, Emrah
dc.date.accessioned2020-03-26T17:26:51Z
dc.date.available2020-03-26T17:26:51Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe purpose of this study was to investigate the beneficial effects of particulate ostrich eggshell grafting on the healing of experimentally induced skull defects. The clinical, radiological, histological, and histomorphometrical findings of this material were compared with the results of commercially available demineralized bone matrix (DBM). The study was conducted on 18 adult New Zealand rabbits. One defect served as a control and the remaining ones either were filled with different sized eggshell particles or DBM, in each animal. Clinical and radiological inspections and histologic investigations of the animals were done at the 1st, 3rd, and 6th months of postoperative period. Radiologically, minimal bone regeneration was observed at the empty, control defect sites. The most advanced bone regeneration was in the DBM grafted defects. The eggshell particle grafted defect sites displayed weak bone regeneration at earlier stages, at 1st and 3rd months after operation when compared with demineralized bone matrix. Nevertheless, ossification was satisfactory at 6th month after operation when compared with the control defects. Within the limitations of this study, it was concluded that Ostrich eggshell powder (OSP) is a worth-while bone substitute because it is a safe, cheap, and easily available material. Long-term studies will clarify its possible role in maxillofacial surgery. Further sophisticated experiments should be undertaken before human implantation concerning its osteoproductive activity alone or in combination with other materials. (C) 2007 Wiley Periodicals, Inc.en_US
dc.identifier.doi10.1002/jbm.b.30990en_US
dc.identifier.endpage89en_US
dc.identifier.issn1552-4973en_US
dc.identifier.issn1552-4981en_US
dc.identifier.issue1en_US
dc.identifier.pmid18076098en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage82en_US
dc.identifier.urihttps://dx.doi.org/10.1002/jbm.b.30990
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22394
dc.identifier.volume86Ben_US
dc.identifier.wosWOS:000256891600010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofJOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectosteoproductive potentialen_US
dc.subjecteggshell powderen_US
dc.subjectbone graft materialen_US
dc.titleEvaluation of the biocompatibility and osteoproductive activity of ostrich eggshell powder in experimentally induced calvarial defects in rabbitsen_US
dc.typeArticleen_US

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