The Effects of Exercise on Antioxidant System and Some Blood Parameters at Experimental Diabetic Rats

Yükleniyor...
Küçük Resim

Tarih

2021 Ağustos

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Selçuk Üniversitesi

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

The aim of this study is to determine the effects of exercise on antioxidant system (MDA, SOD, GSH) and some blood parameteres (plasma insuline, glucose, ALT, AST) in rats with experimental diabetes induced by streptozotocin (STZ). In the study, 32 adult Wistar Albino rats were divided into 4 equal groups as control (C), exercise (E), diabetes (D) and diabetes+exercise (DE). Diabetes was induced in D and DE by intraperitoneal injection with a single dose of 60 mg/kg STZ. After the diabetes was induced, swimming exercise was applied to E and DE for 5 days / 30 min a week for 4 weeks. According to the findings obtained; there was a significant decrease in D and DE compared to C. Plasma glucose levels decreased in DE with exercise in the diabetic groups. While ALT levels increased significantly in diabetic groups compared to others, it was found that exercise did not make a difference in diabetics. However, the increase in AST levels was statistically significant only in D. When serum MDA levels were examined, a significant decrease was observed in DE compared to D. While there was a significant decrease in serum SOD levels in the diabetic groups compared to C. The diabetic groups and DE and E were similar to each other. A significant decrease was observed in GSH levels in D. This difference was also detected between diabetic groups.As a result; in the study it was concluded that regular aerobic exercise improved glycemic control, has a lipid peroxidation-reducing effect and may hava a positive effect on strengthening the antioxidant system in diabetes.

Açıklama

Anahtar Kelimeler

Antioxidants, Exercise, Diabetes Mellitus, Blood Parameters

Kaynak

Turkish Journal of Sport and Exercise

WoS Q Değeri

Scopus Q Değeri

Cilt

23

Sayı

2

Künye

Mehtap, B., Durgun, Z., (2021). The Effects of Exercise on Antioxidant System and Some Blood Parameters at Experimental Diabetic Rats. Turkish Journal of Sport and Exercise, 23(2), 223-229. DOI: 10.15314/tsed.926598