The Effects of Exercise on Antioxidant System and Some Blood Parameters at Experimental Diabetic Rats
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Dosyalar
Tarih
2021 Ağustos
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Selçuk Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The aim of this study is to determine the effects of exercise on antioxidant system (MDA, SOD, GSH) and some blood parameteres (plasma insuline, glucose, ALT, AST) in rats with experimental diabetes induced by streptozotocin (STZ). In the study, 32 adult Wistar Albino rats were divided into 4 equal groups as control (C), exercise (E), diabetes (D) and diabetes+exercise (DE). Diabetes was induced in D and DE by intraperitoneal injection with a single dose of 60 mg/kg STZ. After the diabetes was induced, swimming exercise was applied to E and DE for 5 days / 30 min a week for 4 weeks. According to the findings obtained; there was a significant decrease in D and DE compared to C. Plasma glucose levels decreased in DE with exercise in the diabetic groups. While ALT levels increased significantly in diabetic groups compared to others, it was found that exercise did not make a difference in diabetics. However, the increase in AST levels was statistically significant only in D. When serum MDA levels were examined, a significant decrease was observed in DE compared to D. While there was a significant decrease in serum SOD levels in the diabetic groups compared to C. The diabetic groups and DE and E were similar to each other. A significant decrease was observed in GSH levels in D. This difference was also detected between diabetic groups.As a result; in the study it was concluded that regular aerobic exercise improved glycemic control, has a lipid peroxidation-reducing effect and may hava a positive effect on strengthening the antioxidant system in diabetes.
Açıklama
Anahtar Kelimeler
Antioxidants, Exercise, Diabetes Mellitus, Blood Parameters
Kaynak
Turkish Journal of Sport and Exercise
WoS Q Değeri
Scopus Q Değeri
Cilt
23
Sayı
2
Künye
Mehtap, B., Durgun, Z., (2021). The Effects of Exercise on Antioxidant System and Some Blood Parameters at Experimental Diabetic Rats. Turkish Journal of Sport and Exercise, 23(2), 223-229.
DOI: 10.15314/tsed.926598
