The Effects of Exercise on Antioxidant System and Some Blood Parameters at Experimental Diabetic Rats

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dc.authorid0000-0002-8639-1983en_US
dc.authorid0000-0002-9385-638Xen_US
dc.contributor.authorMehtap, Bekir
dc.contributor.authorDurgun, Zafer
dc.date.accessioned2023-09-09T09:38:16Z
dc.date.available2023-09-09T09:38:16Z
dc.date.issued2021 Ağustosen_US
dc.departmentSelçuk Üniversitesi, Spor Bilimleri Fakültesi, Antrenörlük Eğitimi Bölümüen_US
dc.description.abstractThe aim of this study is to determine the effects of exercise on antioxidant system (MDA, SOD, GSH) and some blood parameteres (plasma insuline, glucose, ALT, AST) in rats with experimental diabetes induced by streptozotocin (STZ). In the study, 32 adult Wistar Albino rats were divided into 4 equal groups as control (C), exercise (E), diabetes (D) and diabetes+exercise (DE). Diabetes was induced in D and DE by intraperitoneal injection with a single dose of 60 mg/kg STZ. After the diabetes was induced, swimming exercise was applied to E and DE for 5 days / 30 min a week for 4 weeks. According to the findings obtained; there was a significant decrease in D and DE compared to C. Plasma glucose levels decreased in DE with exercise in the diabetic groups. While ALT levels increased significantly in diabetic groups compared to others, it was found that exercise did not make a difference in diabetics. However, the increase in AST levels was statistically significant only in D. When serum MDA levels were examined, a significant decrease was observed in DE compared to D. While there was a significant decrease in serum SOD levels in the diabetic groups compared to C. The diabetic groups and DE and E were similar to each other. A significant decrease was observed in GSH levels in D. This difference was also detected between diabetic groups.As a result; in the study it was concluded that regular aerobic exercise improved glycemic control, has a lipid peroxidation-reducing effect and may hava a positive effect on strengthening the antioxidant system in diabetes.en_US
dc.identifier.citationMehtap, B., Durgun, Z., (2021). The Effects of Exercise on Antioxidant System and Some Blood Parameters at Experimental Diabetic Rats. Turkish Journal of Sport and Exercise, 23(2), 223-229. DOI: 10.15314/tsed.926598en_US
dc.identifier.doi10.15314/tsed.926598en_US
dc.identifier.endpage229en_US
dc.identifier.issn2147-5652en_US
dc.identifier.issue2en_US
dc.identifier.startpage223en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/50675
dc.identifier.volume23en_US
dc.institutionauthorMehtap, Bekir
dc.institutionauthorDurgun, Zafer
dc.language.isoenen_US
dc.publisherSelçuk Üniversitesien_US
dc.relation.ispartofTurkish Journal of Sport and Exerciseen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAntioxidantsen_US
dc.subjectExerciseen_US
dc.subjectDiabetes Mellitusen_US
dc.subjectBlood Parametersen_US
dc.titleThe Effects of Exercise on Antioxidant System and Some Blood Parameters at Experimental Diabetic Ratsen_US
dc.typeArticleen_US

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