Is early postradiation dysplasia almost associated with poor prognosis? A case report and review of the literature

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dc.contributor.authorAksu, Maksut Görkem
dc.contributor.authorFayda, M
dc.contributor.authorSaynak, Mert
dc.contributor.authorTore, G
dc.contributor.authorAlatli, C
dc.date.accessioned2020-03-26T17:03:48Z
dc.date.available2020-03-26T17:03:48Z
dc.date.issued2006
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractFollowing radiotherapy for cervical carcinoma, abnormal cytologic changes have been reported in a number of publications. These reactions occur at varying periods of time following irradiation and do not necessarily reflect the presence of invasive cancer. On the basis of cytologic and histopathologic features, these reactions were determined as postradiation dysplasia (PRD). PRD has been reported to occur in 18.7-26% of patients treated by radiotherapy for cervical cancer. In the literature, it was reported that patients diagnosed with PRD less than 3 years after the initial diagnosis of cervical cancer had a mean survival rate of 33.8% as compared with a 100% 5-year survival rate in patients with a delayed (> 3 years) onset of period. We present a case of stage IIIB cervical squamous cell carcinoma with PRD detected 6 months after radiotherapy. The patient is still tumor free 8 years after radiotherapy. In the light of this patient, we review the literature and discuss the relationship of PRD with survival in the cervical carcinomas.en_US
dc.identifier.doi10.1111/j.1525-1438.2006.00216.xen_US
dc.identifier.endpage936en_US
dc.identifier.issn1048-891Xen_US
dc.identifier.issue2en_US
dc.identifier.pmid16681791en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage934en_US
dc.identifier.urihttps://dx.doi.org/10.1111/j.1525-1438.2006.00216.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/20557
dc.identifier.volume16en_US
dc.identifier.wosWOS:000236943200080en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBLACKWELL PUBLISHINGen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCERen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectcervix canceren_US
dc.subjectpostradiation dysplasiaen_US
dc.subjectradiotherapyen_US
dc.titleIs early postradiation dysplasia almost associated with poor prognosis? A case report and review of the literatureen_US
dc.typeReviewen_US

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