Exercise does not increase QTcmax and QTcd in diabetic patients with autonomic neuropathy

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dc.contributor.authorYazıcı, Mehmet
dc.contributor.authorÖzdemir, Kurtuluş
dc.contributor.authorAltunkeser, Bülent Behlül
dc.contributor.authorYazıcı, Raziye
dc.contributor.authorKayrak, Mehmet
dc.contributor.authorÜlgen, Mehmet Sıddık
dc.contributor.authorAlihanoğlu, Yusuf İzzettin
dc.date.accessioned2020-03-26T17:17:27Z
dc.date.available2020-03-26T17:17:27Z
dc.date.issued2007
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: The purpose of this study was to examine the effects of exercise on maximum QTc interval (QTcmax) and QTc dispersion (QTcd) in diabetic patients without clinically evident heart disease. Methods: Seventy-six diabetic patients who had no coronary artery disease or hypertension (group I; mean age 48 +/- 9 years old) and 40 healthy volunteers (group II; mean age 46 +/- 13 years old) were enrolled in the study. Cases with clinically evident heart disease were excluded from the study. Resting 12-lead electrocardiogram (ECG) and maximal treadmill exercise test (according to Bruce protocol) were performed in all cases. The QTcmax interval was determined at rest (RQTcmax) and during peak exercise (PQTcmax). Also, the QTcd was measured at rest (RQTcd) and during peak exercise (PQTcd). Autonomic neuropathy was assessed by measuring the heart rate variability (HRV). Results: There was no significant difference between clinical characteristics of two groups. In group I, HRV parameters were significantly lower than group II. RQTcd, PQTcd, RQTcmax, and PQTcmax were significantly longer in group I (56 +/- 16 vs 34 +/- 11; P < 0.001, 62 +/- 22 vs 40 +/- 15; P < 0.001, respectively). In diabetic patients, there was no significant difference between RQTcmax and PQTcmax (428 +/- 19 vs 420 +/- 31; P > 0.05), and no significant difference was present between RQTcd and PQTcd (56 +/- 16 vs 62 +/- 22; P > 0.05, respectively). Conclusion: Exercise does not affect QTcd in patients with diabetes mellitus and without clinically evident heart disease.en_US
dc.identifier.doi10.1111/j.1540-8159.2007.00897.xen_US
dc.identifier.endpage1498en_US
dc.identifier.issn0147-8389en_US
dc.identifier.issue12en_US
dc.identifier.pmid18070304en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1493en_US
dc.identifier.urihttps://dx.doi.org/10.1111/j.1540-8159.2007.00897.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/21399
dc.identifier.volume30en_US
dc.identifier.wosWOS:000251329400011en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBLACKWELL PUBLISHINGen_US
dc.relation.ispartofPACE-PACING AND CLINICAL ELECTROPHYSIOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectexerciseen_US
dc.subjectcorrected qtmaxen_US
dc.subjectcorrected qtc dispersionen_US
dc.subjectdiabetes mellitusen_US
dc.titleExercise does not increase QTcmax and QTcd in diabetic patients with autonomic neuropathyen_US
dc.typeArticleen_US

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