Does Estimated Glomerular Filtration Rate Have an Effect on Left Ventricular Function after ST-Elevation Myocardial Infarction?

Basit Öğe Kaydı
dc.contributor.authorSonmez, Osman
dc.contributor.authorVatankulu, Mehmet A.
dc.contributor.authorTasal, Abdurrahman
dc.contributor.authorBacaksiz, Ahmet
dc.contributor.authorAyhan, Selim
dc.contributor.authorYazici, Huseyin U.
dc.contributor.authorKarakaya, Ekrem
dc.date.accessioned2020-03-26T18:50:08Z
dc.date.available2020-03-26T18:50:08Z
dc.date.issued2014
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjectivesLittle is known about whether estimated glomerular filtration rates (eGFR) affect left ventricular (LV) function and gain benefit with antiremodeling treatment in patients with ST-elevation myocardial infarction (STEMI). We investigated the effect of eGFR on LV function using tissue Doppler imaging (TDI) parameters. In addition, we sought to evaluate the antiremodeling effect of standard treatment at follow-up in patients with renal insufficiency (RI) after STEMI. Methods and ResultsA retrospective analysis of 579 patients with STEMI was performed. Patients were divided into 3 groups according to eGFR (Group 1: eGFR>90mL/min per 1.73m(2); Group 2: eGFR=60-89mL/min per 1.73m(2); Group 3: eGFR<60mL/min per 1.73m(2)). Conventional echocardiography and TDI were performed within 48-72hours after STEMI and at 6-month follow-up. The mean left ventricular ejection fraction (LVEF) was significantly lower in Group 3 than in Group 1 (P=0.021). The mean peak systolic velocity (Sm) was significantly lower in Group 3 than in Group 1 and Group 2 (P=0.002 and 0.006, respectively). The estimated GFR had a linear association with Sm and LVEF (P=0.001, r=0.161; P=0.005, r=0.132, respectively). Multivariate analysis showed that an eGFR<60mL/min per 1.73m(2) was an independent predictor of lower Sm and in-hospital mortality. In addition, an antiremodeling effect of standard treatment was seen in all groups at 6-month follow-up. ConclusionsEstimated glomerular filtration rate of <60mL/min per 1.73m(2) was associated with lower LV function after STEMI, and may gain an antiremodeling effect with standard treatment at follow-up.en_US
dc.identifier.doi10.1111/echo.12359en_US
dc.identifier.endpage324en_US
dc.identifier.issn0742-2822en_US
dc.identifier.issn1540-8175en_US
dc.identifier.issue3en_US
dc.identifier.pmid24103085en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage318en_US
dc.identifier.urihttps://dx.doi.org/10.1111/echo.12359
dc.identifier.urihttps://hdl.handle.net/20.500.12395/30753
dc.identifier.volume31en_US
dc.identifier.wosWOS:000332346700020en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectacute myocardial infarctionen_US
dc.subjectrenal insufficiencyen_US
dc.subjecttissue Doppleren_US
dc.subjectleft ventricle remodelingen_US
dc.subjectglomerular filtration rateen_US
dc.titleDoes Estimated Glomerular Filtration Rate Have an Effect on Left Ventricular Function after ST-Elevation Myocardial Infarction?en_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu