Testosterone secretion and semen plasma enzyme activity in rams with genital pathology stimulated with GnRH

Basit Öğe Kaydı
dc.contributor.authorAksoy, Melih
dc.contributor.authorKaya, A
dc.contributor.authorVatansev, H
dc.contributor.authorTekeli, T
dc.date.accessioned2020-03-26T16:39:43Z
dc.date.available2020-03-26T16:39:43Z
dc.date.issued2002
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractTestosterone secretion in response to GnRH stimulation and enzymatic activity of semen plasma was evaluated comparatively in rams with or without genital abnormality. Scrota. testes and epididymides of 128 rams between 1.5 and 6 years old from various breeds were examined clinically and ultrasonographically. Bilaterally cryptorchid rams (n = 2), and rams with focal testicular degeneration (n = 3) or unilateral sperm granuloma localized in the caput (n = 3) epididymis or the cauda epididymis (n = 3). diagnosed by either clinical or ultrasonographic examination. were selected for the further investigation of spermatologic parameters, testosterone secretion in response to GnRH stimulation. and enzymatic activity of semen plasma before histopathologic confirmation of lesions. Except for the cryptorchid rams, sperm parameters determined in ejaculates were similar to intact controls (n = 3). GnRH administration increased plasma testosterone levels significantly irrespective of the type of genital pathology (P < 0.01). The testosterone response calculated based on area under the curve following GnRH administration in rams having genital abnormality was not significantly different from the controls. Aspartate aminotransferase (AST) and lactate dehydrogenase (LDH) activity in the semen plasma varied between rams. with the lowest mean values in the bilaterally cryptorchid group (P < 0.05). Spermatic granuloma localized either in the caput or cauda of the epididymis was associated with a significant reduction in the semen plasma AST activity compared to controls (P < 0.01). In conclusion, our results indicated that the ability of testicular tissue to secrete testosterone in response to GnRH stimulation in rains with bilateral cryptorchidisin, focal testicular degeneration and unilateral sperm granuloma was similar to that of intact controls. and that reduced semen plasma AST activity may have a diagnostic value in the diagnosis of the epididymal obstruction in rams. Focal testicular degeneration did not influence AST, alkaline phosphatase (ALP) and LDH activity in semen plasma. (C) 2002 Elsevier Science Inc. All rights reserved.en_US
dc.identifier.doi10.1016/S0093-691X(02)00700-8en_US
dc.identifier.endpage1916en_US
dc.identifier.issn0093-691Xen_US
dc.identifier.issn1879-3231en_US
dc.identifier.issue7en_US
dc.identifier.pmid12041694en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1907en_US
dc.identifier.urihttps://dx.doi.org/10.1016/S0093-691X(02)00700-8
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18054
dc.identifier.volume57en_US
dc.identifier.wosWOS:000175675100014en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE INCen_US
dc.relation.ispartofTHERIOGENOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjecttesticular degenerationen_US
dc.subjectsperm granulomaen_US
dc.subjectcryptorchidismen_US
dc.subjectGnRHen_US
dc.subjecttestosteroneen_US
dc.subjectramen_US
dc.titleTestosterone secretion and semen plasma enzyme activity in rams with genital pathology stimulated with GnRHen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
aksoy2002.pdf
Boyut:
107.27 KB
Biçim:
Adobe Portable Document Format
Açıklama:
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu