Histological evaluation of effectiveness of platelet-rich fibrin on healing of sinus membrane perforations: A preclinical animal study

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dc.contributor.authorAricioglu, Ceyhun
dc.contributor.authorDolanmaz, Dogan
dc.contributor.authorEsen, Alparslan
dc.contributor.authorIsik, Kubilay
dc.contributor.authorAvunduk, Mustafa Cihat
dc.date.accessioned2020-03-26T19:41:50Z
dc.date.available2020-03-26T19:41:50Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate the effectiveness of platelet-rich fibrin (PRF) in repairing of Schneiderian membrane perforations in rabbit maxillary sinus. A total of 42 female New Zealand rabbits were randomly divided into two groups. Symmetrical bony defects were created 1 cm in diameter and the sinus membranes were exposed. The Schneiderian membranes were elevated in both sinuses and each membrane was perforated with a 1 cm incision. No treatment was applied to the right perforations in both groups. Left-sided perforations were closed with collagen membrane in the first group and PRF membrane in the other group. Seven animals randomly selected from each group were sacrificed at weeks 1, 2 and 4 in order to be able to examine the amounts of lymphocytes, fibroblasts, veins, and collagen fibers in the area where the membranes were applied. Histological analyses showed that there were no statistically significant differences between the collagen membrane and the PRF membrane in the healing of sinus perforation area. PRF may be considered as an alternative application to collagen membrane in sinus membrane perforations. (C) 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipSelcuk University, Coordinatorship of Scientific Research ProjectsSelcuk University [10102034]en_US
dc.description.sponsorshipThis study was supported by Selcuk University, Coordinatorship of Scientific Research Projects (grant no. 10102034).en_US
dc.identifier.doi10.1016/j.jcms.2017.05.005en_US
dc.identifier.endpage1157en_US
dc.identifier.issn1010-5182en_US
dc.identifier.issn1878-4119en_US
dc.identifier.issue8en_US
dc.identifier.pmid28596050en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1150en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.jcms.2017.05.005
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35173
dc.identifier.volume45en_US
dc.identifier.wosWOS:000406756400008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCHURCHILL LIVINGSTONEen_US
dc.relation.ispartofJOURNAL OF CRANIO-MAXILLOFACIAL SURGERYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectPlatelet-rich fibrinen_US
dc.subjectSinus floor augmentationen_US
dc.subjectRabbitsen_US
dc.subjectCollagenen_US
dc.subjectFibroblastsen_US
dc.subjectLymphocytesen_US
dc.titleHistological evaluation of effectiveness of platelet-rich fibrin on healing of sinus membrane perforations: A preclinical animal studyen_US
dc.typeArticleen_US

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