Sea rose (Armeria pungens (Link) Hoffmanns. & Link) as a potential source of innovative industrial products for anti-ageing applications
Küçük Resim Yok
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ELSEVIER SCIENCE BV
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
This work explored for the first time the halophyte Armeria pungens (Link) Hoffmann. & Link (sea rose) as a potential source of industrial natural products with anti-ageing potential. In this sense, ethyl acetate, acetone, ethanol and water extracts were prepared from flowers, peduncles and leaves of sea rose and evaluated for in vitro antioxidant capacity by four complementary methods and enzyme inhibitory effects towards enzymes related with the onset of different diseases, namely acetyl-(AChE) and butyrylcholinesterase (BuChE), alpha-glucosidase, tyrosinase, lipase and elastase. The polyphenolic composition of the extracts was appraised by highpressure liquid chromatography coupled with diode array detection analysis (HPLC-DAD). Nineteen phenolic compounds were identified in the extracts, including flavonoids, hydroxybenzoic and hydroxycinnamic acids, and catechin was the main compound detected. The ethanol extract of sea rose leaves was the most effective as DPPH (IC50 = 83.7 mu g/mL) and ABTS (IC50 = 146 mu g/mL) scavenger, and also as a copper chelator (IC50 = 81.8 mu g/mL). The acetone peduncles' extract had the highest iron chelating activity (IC50 = 142 mu g/mL). Water and ethanol leaf extracts showed the uppermost AChE inhibition (water: IC50 = 87.6 mu g/mL; ethanol: IC50 = 90.3 mu g/mL). In turn, the ethanol flower extract had the lowest IC50 values towards a-glucosidase (26.7 mu g/mL) and tyrosinase (268 mu g/mL). The leaf ethanol extract had the highest capacity to inhibit elastase (IC50 = 531 mu g/mL), while none of the extracts had significant inhibitory activity on BuChE and lipase. In conclusion, ethanol extracts from leaves and flowers of sea rose showed to be the most promising source of natural products for industrial applications, with anti-ageing properties, namely neuroprotective, anti-diabetic, anti-wrinkles and anti-melanogenic activities.
Açıklama
Anahtar Kelimeler
Halophytes, Acetylcholinesterase, Antioxidant, alpha-Glucosidase, Tyrosinase, Elastase
Kaynak
INDUSTRIAL CROPS AND PRODUCTS
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
121
