Sea rose (Armeria pungens (Link) Hoffmanns. & Link) as a potential source of innovative industrial products for anti-ageing applications

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dc.contributor.authorRodrigues, Maria J.
dc.contributor.authorPereira, Catarina A.
dc.contributor.authorOliveira, Marta
dc.contributor.authorNeng, Nuno R.
dc.contributor.authorNogueira, Jose M. F.
dc.contributor.authorZengin, Gökhan
dc.contributor.authorMahomoodally, M. Fawzi
dc.date.accessioned2020-03-26T19:55:35Z
dc.date.available2020-03-26T19:55:35Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThis work explored for the first time the halophyte Armeria pungens (Link) Hoffmann. & Link (sea rose) as a potential source of industrial natural products with anti-ageing potential. In this sense, ethyl acetate, acetone, ethanol and water extracts were prepared from flowers, peduncles and leaves of sea rose and evaluated for in vitro antioxidant capacity by four complementary methods and enzyme inhibitory effects towards enzymes related with the onset of different diseases, namely acetyl-(AChE) and butyrylcholinesterase (BuChE), alpha-glucosidase, tyrosinase, lipase and elastase. The polyphenolic composition of the extracts was appraised by highpressure liquid chromatography coupled with diode array detection analysis (HPLC-DAD). Nineteen phenolic compounds were identified in the extracts, including flavonoids, hydroxybenzoic and hydroxycinnamic acids, and catechin was the main compound detected. The ethanol extract of sea rose leaves was the most effective as DPPH (IC50 = 83.7 mu g/mL) and ABTS (IC50 = 146 mu g/mL) scavenger, and also as a copper chelator (IC50 = 81.8 mu g/mL). The acetone peduncles' extract had the highest iron chelating activity (IC50 = 142 mu g/mL). Water and ethanol leaf extracts showed the uppermost AChE inhibition (water: IC50 = 87.6 mu g/mL; ethanol: IC50 = 90.3 mu g/mL). In turn, the ethanol flower extract had the lowest IC50 values towards a-glucosidase (26.7 mu g/mL) and tyrosinase (268 mu g/mL). The leaf ethanol extract had the highest capacity to inhibit elastase (IC50 = 531 mu g/mL), while none of the extracts had significant inhibitory activity on BuChE and lipase. In conclusion, ethanol extracts from leaves and flowers of sea rose showed to be the most promising source of natural products for industrial applications, with anti-ageing properties, namely neuroprotective, anti-diabetic, anti-wrinkles and anti-melanogenic activities.en_US
dc.description.sponsorshipFoundation for Science and Technology (FCT)Portuguese Foundation for Science and Technology; Portuguese National Budget [CCMAR/Multi/04326]; FCTPortuguese Foundation for Science and Technology [SFRH/BD/123658/2016, SFRH/BD/94407/2013, SFRH/BD/116604/2016, SFRH/BPD/86071/2012, UID/MULTI/00612/2013]; FCT Investigator Programme [IF/00049/2012]en_US
dc.description.sponsorshipWork supported by the Foundation for Science and Technology (FCT) and the Portuguese National Budget (CCMAR/Multi/04326 projects). Marta Oliveira also acknowledges FCT for the PhD grant SFRH/BD/123658/2016. Catarina Pereira and Maria Joao Rodrigues acknowledges FCT for the PhD grants SFRH/BD/94407/2013 and SFRH/BD/116604/2016, respectively. Luisa Custodio was supported by FCT Investigator Programme (IF/00049/2012). Nuno R. Neng and Jose M. F. Nogueira also acknowledges FCT for the Post-Doc grant (SFRH/BPD/86071/2012) and funding (UID/MULTI/00612/2013).en_US
dc.identifier.doi10.1016/j.indcrop.2018.05.018en_US
dc.identifier.endpage257en_US
dc.identifier.issn0926-6690en_US
dc.identifier.issn1872-633Xen_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage250en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.indcrop.2018.05.018
dc.identifier.urihttps://hdl.handle.net/20.500.12395/36933
dc.identifier.volume121en_US
dc.identifier.wosWOS:000437996900029en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.relation.ispartofINDUSTRIAL CROPS AND PRODUCTSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectHalophytesen_US
dc.subjectAcetylcholinesteraseen_US
dc.subjectAntioxidanten_US
dc.subjectalpha-Glucosidaseen_US
dc.subjectTyrosinaseen_US
dc.subjectElastaseen_US
dc.titleSea rose (Armeria pungens (Link) Hoffmanns. & Link) as a potential source of innovative industrial products for anti-ageing applicationsen_US
dc.typeArticleen_US

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