Induction of Labor with Vaginal Misoprostol Plus Oxytocin Versus Oxytocin Alone

Yükleniyor...
Küçük Resim

Tarih

2010

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Wiley

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Objective: To compare the effect of an oxytocin infusion alone or preceded by an intravaginal application of misoprostol for labor induction in women with term pregnancies and a low Bishop score. Methods: This study randomized 100 multiparous women with singleton pregnancies over 38 weeks and a Bishop score less than 6 to receive either a single 50-mu g dose of misoprostol intravaginally 3 hours before initiation of the oxytocin infusion or only an oxytocin infusion. The time from induction to delivery, the route of delivery, and maternal and fetal outcomes were analyzed. Results: The mean time from induction to delivery was 9.36 +/- 1.97 hours in the misoprostol plus oxytocin group and 11.08 +/- 3.23 in the oxytocin alone group (P=0.002). The rates of vaginal delivery, 1- and 5-minute Agpar scores, placental abruption, and postpartum hemorrhage were similar between the 2 groups, as were the rates of admission to the neonatal intensive care unit. There were no cases of perinatal asphyxia. Conclusion: A 50-mu g intravaginal application of misoprostol before starting the oxytocin infusion is a more effective method of labor induction than an oxytocin infusion alone for our study population.

Açıklama

Anahtar Kelimeler

Induction of labor, Misoprostol, Oxytocin

Kaynak

International Journal of Gynecology & Obstetrics

WoS Q Değeri

Q2

Scopus Q Değeri

Q1

Cilt

110

Sayı

Künye

Balcı, O., Mahmoud, A. S., Özdemir, S., Acar, A., (2010). Induction of Labor with Vaginal Misoprostol Plus Oxytocin Versus Oxytocin Alone. International Journal of Gynecology & Obstetrics, (110), 64-67. Doi: 10.1016/j.ijgo.2010.02.004