Effects of exercise training on hepatic oxidative stress and antioxidant status in aged rats

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dc.contributor.authorOkudan, Nilsel
dc.contributor.authorBelviranli, Muaz
dc.date.accessioned2020-03-26T19:23:49Z
dc.date.available2020-03-26T19:23:49Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThis study investigated the effects of exercise training on oxidative stress, and antioxidant defense markers in the liver tissues of young and aged rats. Two age groups of 4-(young) and 20-months-(aged) old male Wistar rats were performed exercise training program consisted of swimming exercise for 8 weeks. The biomarkers of pro/antioxidant status malondialdehyde (MDA), protein carbonyl (PC), 8-hydroxy-2-deoxyguanosine (8-OHdG), total glutathione (GSH) and superoxide dismutase (SOD) were assessed by commercially available kits. PC levels were higher in the untrained aged rats compared to the young groups and exercise training decreased PC levels (p<0.05). 8-OHdG levels were higher in the aged groups (p<0.05). MDA and GSH levels and SOD activity did not differ significantly between the groups (p>0.05). The present findings indicate that exercise training prevents aging-induced hepatic oxidative damage especially in the proteins.en_US
dc.identifier.doi10.1080/13813455.2016.1199574en_US
dc.identifier.endpage185en_US
dc.identifier.issn1381-3455en_US
dc.identifier.issn1744-4160en_US
dc.identifier.issue4en_US
dc.identifier.pmid27424521en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage180en_US
dc.identifier.urihttps://dx.doi.org/10.1080/13813455.2016.1199574
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33505
dc.identifier.volume122en_US
dc.identifier.wosWOS:000386831100002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectExerciseen_US
dc.subjectagingen_US
dc.subjectliveren_US
dc.subjectoxidative damageen_US
dc.subjectantioxidant defenseen_US
dc.titleEffects of exercise training on hepatic oxidative stress and antioxidant status in aged ratsen_US
dc.typeArticleen_US

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