Cerebral venous thrombosis is associated with major vessel disease in Behcet's syndrome

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dc.contributor.authorTunc, R
dc.contributor.authorSaip, S
dc.contributor.authorSiva, A
dc.contributor.authorYazici, H
dc.date.accessioned2020-03-26T16:47:58Z
dc.date.available2020-03-26T16:47:58Z
dc.date.issued2004
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: To examine the association between the type of central nervous system (CNS) involvement (parenchymal disease and cerebral venous thrombosis (CVT)) and extra-cranial large vessel events, mainly venous thrombosis, in Behcet's syndrome (BS). Methods: Conventional venous angiograms, Doppler ultrasonography, computed tomography, and MR angiography were used to study 88 patients with BS, with (n = 88) and without ( n = 80) CNS disease for the presence of major vessel disease. Results: Major vessel involvement among the male patients with and without CNS disease (21/73 (29%) v 18/80 (23%), respectively) showed no significant differences (p = 0.374). When patients with CNS disease were stratified according to the type of CNS involvement, 7/11 (64%) patients with CVT had major vessel disease compared with 15/77 (19%) patients with parenchymal disease (p = 0.004). The mean (SD) age of onset of CVT (23.1 (8.8) years) among the male patients was significantly earlier than among the men with parenchymal disease (32.0 (7.5); p = 0.002). Conclusions: CVT in BS was strongly associated with peripheral major vessel disease and occurred earlier in the disease course than the parenchymal type of CNS disease. As superficial thrombophlebitis also occurs more frequently in patients with major vessel disease in BS, this may suggest a common pathogenic mechanism.en_US
dc.identifier.doi10.1136/ard.2003.018515en_US
dc.identifier.endpage1694en_US
dc.identifier.issn0003-4967en_US
dc.identifier.issn1468-2060en_US
dc.identifier.issue12en_US
dc.identifier.pmid15547099en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1693en_US
dc.identifier.urihttps://dx.doi.org/10.1136/ard.2003.018515
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18963
dc.identifier.volume63en_US
dc.identifier.wosWOS:000225161700032en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBMJ PUBLISHING GROUPen_US
dc.relation.ispartofANNALS OF THE RHEUMATIC DISEASESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleCerebral venous thrombosis is associated with major vessel disease in Behcet's syndromeen_US
dc.typeArticleen_US

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