Functional innervation of the isolated bowel segment

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dc.contributor.authorGünel, Engin
dc.contributor.authorŞahin, Ayşe
dc.contributor.authorÇağlayan, Fatma
dc.contributor.authorAkıllıoğlu, İshak
dc.date.accessioned2020-03-26T16:27:09Z
dc.date.available2020-03-26T16:27:09Z
dc.date.issued1999
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractPurpose: The aim of this study is to investigate whether there might be an eventual change in the enteric nerve responses to electrical field stimulation (EFS) of the isolated bowel segment (IBS) created by omentoenteropexy. Methods: In the experimental group, an IBS was created in 10 rats using the omentum as the host organ by dividing of its mesentery 4 weeks later. In the control group, a jejunal loop of identical site and length to the IBS was studied in another 10 rats as normal jejunal segment. Longitudinal muscle strips were prepared from the IBSs (n = 20) and the normal jejunal segments (n = 20). The effects of atropine, tetrodotoxin, L-arginine, and L-nitroarginine methyl ester (L-NAME) on the responses to transmural EFS were examined in both the IBS and normal jejunal segment using the isometric tension recording technique. Results: Transmural EFS of the IBS strips produced contractile responses. Atropine and tetrodotoxin abolished the EFS-induced contractions of the IBS. Moreover, EFS-induced contractions were increased by the application of L-NAME, and were decreased by the application of L-arginine in the IBS. Mean percent change of IBS's contraction was not found statistically different from mean percent change of normal jejunal segment's contraction on the effects of L-NAME and L-arginine. Conclusion: These results suggest that the IBS, created by omentoenteropexy, produced enteric nerve responses to EFS as seen as in normal jejunal segment. Copyright (C) 1999 by W.B. Saunders Company.en_US
dc.identifier.doi10.1016/S0022-3468(99)90482-7en_US
dc.identifier.endpage389en_US
dc.identifier.issn0022-3468en_US
dc.identifier.issue3en_US
dc.identifier.pmid10211637en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage387en_US
dc.identifier.urihttps://dx.doi.org/10.1016/S0022-3468(99)90482-7
dc.identifier.urihttps://hdl.handle.net/20.500.12395/16952
dc.identifier.volume34en_US
dc.identifier.wosWOS:000079227500003en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B SAUNDERS COen_US
dc.relation.ispartofJOURNAL OF PEDIATRIC SURGERYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectisolated bowel segmenten_US
dc.subjectomentoenteropexyen_US
dc.subjectfunctional innervationen_US
dc.titleFunctional innervation of the isolated bowel segmenten_US
dc.typeArticleen_US

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