Impact of anatomical features of the left atrial appendage on outcomes after cryoablation for atrial fibrillation

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dc.contributor.authorKocyigit, Duygu
dc.contributor.authorYalcin, Muhammed Ulvi
dc.contributor.authorGurses, Kadri Murat
dc.contributor.authorTurk, Gamze
dc.contributor.authorArdali, Selin
dc.contributor.authorCanpolat, Ugur
dc.contributor.authorEvranos, Banu
dc.contributor.authorYorgun, Hikmet
dc.contributor.authorHazirolan, Tuncay
dc.contributor.authorAytemir, Kudret
dc.date.accessioned2020-03-26T20:14:35Z
dc.date.available2020-03-26T20:14:35Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAims: Pulmonary vein isolation (PVI) using cryoballoon has been accepted as a safe and effective method for treatment of atrial fibrillation (AF). Despite advances in catheter-based technologies, some patients still experience AF recurrence. In this study, we aimed to compare left atrial appendage (LAA) morphology in AF patients and subjects with sinus rhythm and also investigate the association between LAA morphology and success of PVI using cryoballoon in subjects with AF. Methods: In this prospective study, 359 AF patients who underwent pre-ablation computed tomographic angiography (CTA) scan between January 2013-March 2016 were included as the patient group. 100 age and gender-matched subjects in sinus rhythm who had no AF episodes in 24-h Holter monitoring that underwent CTA were included as the control group. Results: Non-chicken wing LAA morphology was more common in AF patients (p < 0.001). LAA was significantly deeper (p < 0.001) and short-axis diameter of LAA orifice and LAA orifice area were significantly larger (p < 0.001) in AF patients. Low take-off type morphology of LAA was more common in controls compared to AF patients (p = 0.006). At a median follow-up of 37 months, only longitudinal-axis left atrial diameter on CT (p = 0.003) and cauliflower-type LAA morphology (p = 0.004) were independent predictors of AF recurrence. Conclusion: This is the first study in the literature that investigates the relationship between anatomical variations of LAA and AF recurrence following cryoablation. Our findings demonstrate that cauliflower-type LAA morphology is associated with two-fold increased risk of AF recurrence.en_US
dc.identifier.citationKocyigit, D., Yalcin, M. U., Gurses, K. M., Turk, G., Ardali, S., Canpolat, U., Evranos, B., Yorgun, H., Hazirolan, T., Aytemir, K. (2019). Impact Of Anatomical Features Of The Left Atrial Appendage On Outcomes After Cryoablation For Atrial Fibrillation. Journal Of Cardiovascular Computed Tomography, 13,(2), 105-112.
dc.identifier.doi10.1016/j.jcct.2019.01.011en_US
dc.identifier.endpage112en_US
dc.identifier.issn1934-5925en_US
dc.identifier.issue2en_US
dc.identifier.pmid30639114en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage105en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.jcct.2019.01.011
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37903
dc.identifier.volume13en_US
dc.identifier.wosWOS:000469323800009en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYalcin, Muhammed Ulvi
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE INCen_US
dc.relation.ispartofJOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectMultidetector computed tomographyen_US
dc.subjectAtrial fibrillationen_US
dc.subjectCryoablationen_US
dc.subjectLeft atrial appendageen_US
dc.subjectMorphologyen_US
dc.titleImpact of anatomical features of the left atrial appendage on outcomes after cryoablation for atrial fibrillationen_US
dc.typeArticleen_US

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