A novel platelet concentrate for guided bone regeneration: Titanium prepared platelet-rich fibrin (T-PRF)

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dc.contributor.authorTunalı, Mustafa
dc.contributor.authorÖzdemir, Hakan
dc.contributor.authorKüçükodacı, Zafer
dc.contributor.authorEzirganlı, Şeref
dc.contributor.authorBarış, Emre
dc.contributor.authorAkman, Serhan
dc.contributor.authorAtay, Arzu
dc.date.accessioned2020-03-26T19:08:10Z
dc.date.available2020-03-26T19:08:10Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn our previous studies, we developed a novel platelet-rich product that we called titaniumprepared platelet-rich fibrin (T-PRF). T-PRF is based on the hypothesis that titanium may be more effective at activating platelets than the silica activators used with glass tubes in Chouckroun's platelet-rich fibrin (PRF). This study aimed to assess the effects of T-PRF on bone augmentation in a rabbit calvaria model. Twenty-four adult male New Zealand rabbits were used in the study. T-PRF alone, inorganic bovine bone (ABB), and T-PRF + ABB were used in the experimental groups. No material was used in the control group. Half of the animals were sacrificed after one month, and the remaining animals were sacrificed 3 months later. A histomorphometric evaluation was performed to compare new bone formation among the groups. More new bone areas were determined in the T-PRF group than the other three groups. While less new bone formation was observed than in the T-PRF group, more new bone formation occurred in the ABB and T-PRF + ABB groups when compared to the control group. Basing on the results of this study, we can say that T-PRF membrane can be successfully used for bone augmentation. © Gülhane Askeri Tip Akademisi 2015.en_US
dc.identifier.doi10.5455/gulhane.173504en_US
dc.identifier.endpage106en_US
dc.identifier.issn1302-0471en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage102en_US
dc.identifier.urihttps://dx.doi.org/10.5455/gulhane.173504
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32790
dc.identifier.volume57en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherGulhane Medical School, University of Health Sciencesen_US
dc.relation.ispartofGulhane Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectBiomaterial(s)en_US
dc.subjectGuided bone regenerationen_US
dc.subjectRegenerative medicineen_US
dc.subjectT-PRFen_US
dc.subjectTissue engineeringen_US
dc.titleA novel platelet concentrate for guided bone regeneration: Titanium prepared platelet-rich fibrin (T-PRF)en_US
dc.typeArticleen_US

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