The Effect of Low Dose Zinc Supplementation to Serum Estrogen and Progesterone Levels in Post-menopausal Women

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dc.contributor.authorSunar, Fusun
dc.contributor.authorGormus, Zulfikare Isik
dc.contributor.authorBaltaci, Abdulkerim Kasim
dc.contributor.authorMogulkoc, Rasim
dc.date.accessioned2020-03-26T17:28:03Z
dc.date.available2020-03-26T17:28:03Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe objective of the present study is to investigate how low-dose zinc supplementation for 2 weeks in the post-menopausal period influences levels of estrogen and progesterone in the serum. The study registered 32 natural menopause patients, who were allocated to four groups with equal number of patients. Group 1, control group, which was not subjected to any procedure. Group 2, the group that was supplemented with 15 mg/day zinc sulfate for 2 weeks. Group 3, the group that was given hormone replacement therapy (0.625 mg estrogen+ 5 mg medroxyprogesterone acetate/day) for 2 weeks. Group 4, the group that received hormone replacement therapy (0.625 mg estrogen+5 mg medroxyprogesterone acetate/day) and zinc sulfate (15 mg/day) for 2 weeks. Blood samples were collected twice from each subject, once at the beginning of the study, and once at the end of the 4-week procedure to determine estrogen (E2) and progesterone levels. Variance analysis was employed in the statistical evaluation of data. Level of significance was set at p < 0.05. No significant difference was found between the estrogen and progesterone levels of groups 1 and 2. Groups 3 and 4 had higher estrogen and progesterone levels than groups 1 and 2 (p < 0.05). Estrogen and progesterone levels in groups 3 and 4 were not different. Results of the study show that low-dose zinc supplementation to post-menopausal women for 2 weeks does not have a significant effect on the concerned parameters.en_US
dc.identifier.doi10.1007/s12011-008-8211-yen_US
dc.identifier.endpageS14en_US
dc.identifier.issn0163-4984en_US
dc.identifier.pmid18759067en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpageS11en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s12011-008-8211-y
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22703
dc.identifier.volume126en_US
dc.identifier.wosWOS:000262202700002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHUMANA PRESS INCen_US
dc.relation.ispartofBIOLOGICAL TRACE ELEMENT RESEARCHen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectLow-dose zinc supplementationen_US
dc.subjectEstrogenen_US
dc.subjectProgesteroneen_US
dc.titleThe Effect of Low Dose Zinc Supplementation to Serum Estrogen and Progesterone Levels in Post-menopausal Womenen_US
dc.typeArticleen_US

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