Evaluation of hematological parameters in children with FMF

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dc.authorid0000-0001-5478-1197
dc.contributor.authorYorulmaz, Alaaddin
dc.contributor.authorAkbulut, Hikmet
dc.contributor.authorTaş, Suna Adeviye
dc.contributor.authorTıraş, Merve
dc.contributor.authorYahya, İbaa
dc.contributor.authorPeru, Harun
dc.date.accessioned2020-03-26T20:14:02Z
dc.date.available2020-03-26T20:14:02Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractIn this study, we aimed to investigate whether neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and mean platelet volume (MPV) might be helpful in the diagnosis of subclinical inflammation of familial Mediterranean fever (FMF). Clinical, laboratory, and genetic results of the patients who were followed up with the diagnosis of FMF were obtained retrospectively from the hospital files and recorded to standardized form. Age- and sex-matched healthy subjects were included as the control group. Eighty-three of the 143 patients (58.0%) were male and 60 (42.0%) were female. The mean age of our patients was 164.62 +/- 51.20months and the mean age of the control group was 164.92 +/- 51.10months. The mean diagnosis age of our patients was 98.10 +/- 49.11months. The mean follow-up time of the patients was 66.03 +/- 36.37months. 91.60% of our patients had abdominal pain, 78.32% fever, and 28.67% joint pain. The mean NLR of the patients was significantly higher than the mean levels at attack-free period and the control group. However, no statistically significant difference was found between the mean levels at attack-free period and the control group. MPV levels were statistically significantly high during acute attack when compared with the control group. However, they showed no statistically significant difference between acute attack and attack-free period. NLR is a useful marker to predict inflammation in FMF patients. However, our results did not support the idea that MPV might reflect acute attack and attack-free period.en_US
dc.identifier.citationYorulmaz, A., Akbulut, H., Taş, S. A., Tıraş, M., Yahya, İ., Peru, H. (2019). Evaluation of Hematological Parameters in Children with FMF. Clinical Rheumatology, 38(3), 701-707.
dc.identifier.doi10.1007/s10067-018-4338-1en_US
dc.identifier.endpage707en_US
dc.identifier.issn0770-3198en_US
dc.identifier.issn1434-9949en_US
dc.identifier.issue3en_US
dc.identifier.pmid30328023en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage701en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s10067-018-4338-1
dc.identifier.urihttps://hdl.handle.net/20.500.12395/37809
dc.identifier.volume38en_US
dc.identifier.wosWOS:000460116500010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYorulmaz, Alaaddin.
dc.institutionauthorAkbulut, Hikmet.
dc.institutionauthorTaş, Suna Adeviye.
dc.institutionauthorTıraş, Merve.
dc.institutionauthorYahya, İbaa.
dc.institutionauthorPeru, Harun.
dc.language.isoenen_US
dc.publisherSPRINGER LONDON LTDen_US
dc.relation.ispartofCLINICAL RHEUMATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAttacken_US
dc.subjectChilden_US
dc.subjectFamilial Mediterranean feveren_US
dc.subjectInflammationen_US
dc.titleEvaluation of hematological parameters in children with FMFen_US
dc.typeArticleen_US

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