Antioxidant properties and enzyme inhibitory effects of extracts from Mandragora autumnalis and its fatty acid composition
Yükleniyor...
Dosyalar
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
MARMARA UNIV, FAC PHARMACY
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The present research was undertaken to evaluate antioxidant activities and enzyme inhibitory potentials of two extracts from two parts of Mandragora autumnalis. The antioxidant properties were evaluated by using different methods [ABTS (2,2-azino-bis (3-ethylbenzothiazloine-6-sulphonic acid)), DPPH (1,1 diphenyl-2-picrylhydrazyl radical), CUPRAC (cupric ion reducing antioxidant capacity), and FRAP (ferric reducing antioxidant power assays)]. Enzyme inhibitory potentials were tested against cholinesterase (AChE and BChE), tyrosinase, a-amylase and a-glucosidase. For phytochemical composition, fatty acids, total phenolics and flavonoid content were investigated. Generally F-Met exhibited the strongest antioxidant effect with the highest level of phenolics. Total phenolic and flavonoid content were determined as 26.10-46.92 mgGAE/g abd 3.60-26.11 mgRE/g, respectively. a- linolenic acid was found to be major fatty acids in the studied oils (33.81 % for flowers and 39.15 % for leaves). The study suggested that M. autumnalis could be valuable as a source of natural agents in food and pharmaceutical applications.
Açıklama
Anahtar Kelimeler
antioxidant activity, enzyme inhibitory activity, Mandragora autumnalis, phenolic compounds
Kaynak
Marmara Pharmaceutical Journal
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
20
Sayı
2
Künye
Uysal, S., Zengin, G., Aktumsek, A. (2016). Antioxidant Properties and Enzyme Inhibitory Effects of Extracts from Mandragora Autumnalis and its Fatty Acid Composition. Marmara Pharmaceutical Journal, 20(2), 522-529.
