Antioxidant properties and enzyme inhibitory effects of extracts from Mandragora autumnalis and its fatty acid composition

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dc.contributor.authorUysal, Şengül
dc.contributor.authorZengin, Gökhan
dc.contributor.authorAktümsek, Abdurrahman
dc.date.accessioned2020-03-26T19:23:06Z
dc.date.available2020-03-26T19:23:06Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesi, Fen Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractThe present research was undertaken to evaluate antioxidant activities and enzyme inhibitory potentials of two extracts from two parts of Mandragora autumnalis. The antioxidant properties were evaluated by using different methods [ABTS (2,2-azino-bis (3-ethylbenzothiazloine-6-sulphonic acid)), DPPH (1,1 diphenyl-2-picrylhydrazyl radical), CUPRAC (cupric ion reducing antioxidant capacity), and FRAP (ferric reducing antioxidant power assays)]. Enzyme inhibitory potentials were tested against cholinesterase (AChE and BChE), tyrosinase, a-amylase and a-glucosidase. For phytochemical composition, fatty acids, total phenolics and flavonoid content were investigated. Generally F-Met exhibited the strongest antioxidant effect with the highest level of phenolics. Total phenolic and flavonoid content were determined as 26.10-46.92 mgGAE/g abd 3.60-26.11 mgRE/g, respectively. a- linolenic acid was found to be major fatty acids in the studied oils (33.81 % for flowers and 39.15 % for leaves). The study suggested that M. autumnalis could be valuable as a source of natural agents in food and pharmaceutical applications.en_US
dc.identifier.citationUysal, S., Zengin, G., Aktumsek, A. (2016). Antioxidant Properties and Enzyme Inhibitory Effects of Extracts from Mandragora Autumnalis and its Fatty Acid Composition. Marmara Pharmaceutical Journal, 20(2), 522-529.
dc.identifier.doi10.12991/mpj.201620206523en_US
dc.identifier.endpage151en_US
dc.identifier.issn1309-0801en_US
dc.identifier.issue2en_US
dc.identifier.pmid#YOKen_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage144en_US
dc.identifier.urihttps://dx.doi.org/10.12991/mpj.201620206523
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33269
dc.identifier.volume20en_US
dc.identifier.wosWOS:000379969900013en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorUysal, Şengül
dc.institutionauthorZengin, Gökhan
dc.institutionauthorAktümsek, Abdurrahman
dc.language.isoenen_US
dc.publisherMARMARA UNIV, FAC PHARMACYen_US
dc.relation.ispartofMarmara Pharmaceutical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectantioxidant activityen_US
dc.subjectenzyme inhibitory activityen_US
dc.subjectMandragora autumnalisen_US
dc.subjectphenolic compoundsen_US
dc.titleAntioxidant properties and enzyme inhibitory effects of extracts from Mandragora autumnalis and its fatty acid compositionen_US
dc.typeArticleen_US

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